Betaine hydrochloride, the all-star ingredient in HCl Breakthrough, is a form of betaine, a B vitamin-like substance, that releases hydrochloric acid once it dissolves in water. It increases stomach acidity in those with low stomach acid, lowering the pH of the stomach towards a more acidic environment for short periods of time [7, 8]. This makes it an ideal ingredient for those who struggle with post-meal digestive discomfort due to suboptimal stomach acid.

For individuals who may not produce optimal levels of stomach acid, Betaine HCl can help support digestion by promoting a more acidic gastric environment. Having enough stomach acid is key to digestion, nutrient absorption, and healthy gut microbial balance

Proteases are a small group of enzymes that work to break down proteins into smaller peptides and amino acids for better absorption. Studies show that protease supplementation is able to enhance protein digestion and absorption. One study in 24 healthy adults given protease in combination with a high protein meal found that those who took proteases had significantly higher total amino acid levels over a 5-hour period compared to the placebo group [9].

The proteases in HCl Breakthrough are from plant-based sources, unlike several digestive products that use porcine or bovine pepsin. Protease 3.0, combined with betaine HCl, improves overall protein digestion in the stomach. Whereas, protease 4.5 is ideal for protein digestion in those with suboptimal stomach acidity.

Amylase is a digestive enzyme that helps break down carbohydrates, especially starches [10]. Starches are long molecules that can be difficult for the body to break down, and amylase helps break them down into simpler sugars that your body can readily take up.

One study examined amylase supplementation in combination with probiotics and found that those who took it experienced a reduction in occasional bloating and digestive discomfort and the degree to which digestive symptoms impacted quality of life [11].

We included amylase in our formula to help optimize digestion in combination with betaine HCl, to help improve carbohydrate digestion and possibly symptoms like occasional bloating that can happen when starches are not completely broken down.

Lipase is a key enzyme required to break down fats into fatty acids and glycerol. Studies find that taking a lipase supplement prior to a high-fat meal can help reduce feelings of fullness [12].

In combination with Betaine HCl, lipase helps promote the breakdown and absorption of dietary fats, which might mitigate occasional digestive discomfort from a high-fat meal.

Cellulase is a digestive enzyme that helps your body break down cellulose, a component in plant cell walls. Humans normally do not have the ability to break down cellulose, which may contribute to occasional bloating, gas, or stomach discomfort when eating high-fiber foods like vegetables and whole grains. Cellulase supplementation might make it easier for your body to process these high-fiber foods, and better absorb nutrients from plant-based products.

Trace minerals such as zinc, copper, magnesium, and molybdenum work as cofactors in several metabolic and digestive enzymes. By providing a small amount of trace minerals, HCL Breakthrough can help ensure optimal digestive enzyme functions.

HCL Breakthrough is not just any betaine HCl supplement. It’s a comprehensive blend of betaine HCl, five digestive enzymes, and a trace mineral blend that provides enzyme cofactors. This makes it a comprehensive stomach function support.

Betaine HCl helps promote the key acidic environment to kickstart the digestive process while improving the digestion of all macronutrients. This enhances overall digestion and absorption and digestive wellness commonly linked to suboptimal stomach acid.

Begin by taking one capsule with a protein-containing meal. If no discomfort or burning occurs, you can increase the dose to two capsules with your next protein-containing meal. If tolerated, you can continue using this dose as needed.

As with any supplement, the appropriate amount may vary depending on individual digestive needs. If you notice any warmth or digestive discomfort, consider reducing your intake. Over time, some individuals find they need less as their digestion improves [13].

It is important to avoid taking HCL Breakthrough on an empty stomach or if you have any contraindications listed below. Without food to break down, the enzymes in the supplement can cause nausea or stomach discomfort. Therefore, it is best taken within the first few bites of food, or within 30 minutes of eating a meal.