Finally,

A Perimenopause System Built To Support It All.

All 5 Formulas. Up To 20% Off

Science-Backed Support for Sleep, Stress, Digestion, and Focus

  • Digestion / Energy

  • All-Day / All Night

  • Daily Balance

  • Magnesium Breakthrough
    Chill Pills

    Want great restful sleep?

    All 7 forms of magnesium work together to support whole-body health.*
  • MassZymes
    3x The Value of Food

    Want to get all the nutrients from your food?

    Get the most potent enzymes blend to break down food, improve digestive function, and nutrient absorption.
  • Probiotic Breakthrough
    Probiotics’ Elite Special Forces

    Want to protect your body from pathogens and bad bacteria?

    This prebiotic and probiotic super-strain gives you a strong defence for a healthy gut and immune function.
  • Berberine Breakthrough
    Carb Crusher

    Want to optimize your blood sugar response?

    Balance blood sugar levels and improve carbohydrate uptake into muscles rather than fat cells.
  • Sleep Breakthrough
    Sweet Dreams

    Want to stay asleep all night and wake up energized?

    Get the best sleep of your life by activating all 5 sleep pathways.

  • Stress Guardian
    Shield Your Body & Mind From Stress

    Want to protect your body from the relentless onslaught of stress?

    Our innovative formula boosts your natural resilience, fostering a balance of HPA axis for calm, focused control.

  • The Perimenopause Daily Support Bundle
    helps your body’s key systems work in harmony.

    Each product has a clear purpose and
    role in your daily routine:

    • Magnesium Breakthrough
      nervous system & relaxation*
    • Stress Guardian
      Supports Stress Response & Daily Resilience*
    • Sleep Breakthrough
      Healthy Sleep Cycles & Nighttime Recovery*
    • Probiotic Breakthrough
      Gut Health & Digestive Balance*
    • Berberine Breakthrough
      Metabolic Health*

Recommended by Top Health Experts & Performers

Chalene Johnson

“Magnesium is essential for everything—sleep, energy, hormones, and more. Magnesium Breakthrough gives me all the types I need in one formula. Take this daily! ”

Melanie Avalon

As a biohacker, podcaster, and health influencer, I cannot recommend Probiotic Breakthrough enough! On my high-protein diet, I can literally feel the difference in my digestion and energy.

Elizabeth Skordinski

BIOptimzers products are exceptional and have changed my health in so many ways. I am so grateful for BIOptimizers!

Cynthia Thurlow

When I think about foundational supplements we can all benefit from I think a great deal about digestive enzymes and the best product that I've ever used is MassZymes by BIOptimizers

The 365 Day "Best Product Ever Or Your Money Back" Guarantee

All BIOptimizers products come with a 365-Day Money Back Guarantee. If you are not completely satisfied with your BIOptimizers product for any reason between today and 365 days from now, just send back your remaining unopened bottles of the product and we'll give you a full refund (minus the cost of shipping and handling). If you open a second bottle, you no longer qualify for any guarantee. Reach out to our customer happiness team and they will take complete care of it.