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Magnesium Breakthrough Advanced 10

10 Bioavailable Forms · 550mg Elemental Magnesium · P5P + Ionic Trace Minerals

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60 capsules

10 bioavailable forms of magnesium for complete, whole-body support*
Supports relaxation & restorative sleep*
550mg of elemental magnesium per serving
Promotes a healthy stress response*
Helps maintain healthy metabolic health*
Supports muscle function & recovery

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Our Most Advanced Magnesium Breakthrough

Evolution is in our DNA. So we decided to see if we could push the science even further.

We tracked down every new form of magnesium we could find and tested them one by one. Then we tested combinations, with the goal of maximizing bioaccessibility and bioavailability to design the most complete, whole-body magnesium support.

Two years and 5,500 experiments later, we finally cracked the code.

We’ve gone from 7 magnesium forms to 10.
We increased elemental magnesium from 500mg per serving to 550mg.
And here’s the big one: we nearly doubled bioaccessibility in our laboratory results.

What this means is that we may be helping your body access more magnesium in every serving.*

Why Did We Include 10 Forms of Magnesium?

Because if you want complete support for more restorative sleep, metabolic health, muscle recovery, and a healthy stress response, you need multi-pathway support.

Think of single-form magnesium as one key for one lock. Magnesium Breakthrough Advanced carries 10 keys to unlock more doors, helping provide broad-spectrum magnesium support across multiple systems of the body.*

MAGNESIUM GLYCINATE

Magnesium glycinate helps support muscle relaxation and a sense of calm.*
MAGNESIUM CITRATE

Magnesium citrate supports energy metabolism, meaning how your body creates and uses energy.* It may also help support healthy blood vessel function in healthy individuals.*
MAGNESIUM TAURATE

Magnesium taurate supports healthy cardiovascular function.* Research suggests it may also help support healthy circulation.*
MAGNESIUM CHELATE

Magnesium chelate supports healthy muscle function and balanced muscle tone.*
MAGNESIUM OROTATE

Magnesium orotate supports cellular energy and metabolic processes.* Because of its role in energy production, it is often used to support exercise recovery and performance.*
MAGNESIUM MALATE

Magnesium malate is a bioavailable form of magnesium and is naturally linked to compounds found in fruits. It supports energy production and muscle function.*
SUCROSOMIAL® MAGNESIUM

Sucrosomial® magnesium is designed to support magnesium delivery, helping make more magnesium available.* It also supports immune system health and bone health.*

PLUS 3 MORE TO ROUND OUT THE COMPLETE FORMULA

MAGNESIUM BHB

Magnesium BHB combines magnesium with beta-hydroxybutyrate, a naturally occurring ketone body involved in energy metabolism.*
MAGNESIUM CAPRYLATE

Magnesium caprylate combines magnesium with caprylic acid (C8), a medium-chain fatty acid known for its distinct metabolic properties.*
MAGNESIUM ASPARTATE

Magnesium aspartate, an amino-acid chelated form included as part of the formula’s diverse magnesium blend.*

Find Your Magnesium Breakthrough

Forms Of Magnesium

7 Forms

8 Forms

10 Forms

Amount of Magnesium

500mg Elemental Magnesium

325mg Elemental Magnesium

550mg Elemental Magnesium

Best For

Foundational support for everyday sleep and stress

A calming ritual you can look forward to drinking any time of day or night*

Most complete whole-body support for heavy stress, sleep disruption, travel, or when life demands more from you

What it Does

Supports sleep, relaxation, stress resilience, and recovery*

Supports calm, sleep, and stress resilience in a delicious drinkable form*

Supports restorative sleep, relaxation, stress resilience, recovery, and metabolic health*

Learn More

WHY MAGNESIUM BREAKTHROUGH ADVANCED 10

Magnesium supports hundreds of functions throughout the body — energy production, muscle function, nervous system activity, cardiovascular physiology, glucose metabolism, bone health, immune function, and healthy sleep physiology.*

Yet many adults don’t get enough through diet alone. Modern eating habits, processed foods, agricultural practices, stress, aging, physical activity, and certain medications can all increase the body’s demand for magnesium.*

Most magnesium supplements rely on only one or two forms. But magnesium compounds differ — in solubility, gastrointestinal tolerance, dissolution behavior, and bioaccessibility. That’s why Advanced 10 combines 10 complementary forms rather than depending on a single source.*

Advanced 10 delivers:

10 complementary forms of magnesium
550 mg elemental magnesium per serving
Active vitamin B6 as Pyridoxal-5-Phosphate (P5P)
Ionic trace minerals
Identity, bioaccessibility, and bioavailability testing built into formulation*

The goal isn’t just to provide magnesium — it’s to support whole-body magnesium status through thoughtfully selected, complementary ingredients.*

INGREDIENTS

Vitamin B6 (as Pyridoxine-5-Phosphate), Magnesium Proprietary Blend (Magnesium Chelate, Magnesium Glycinate, Sucrosomial® Magnesium (as Magnesium Oxide), Magnesium Malate, Magnesium Orotate, Magnesium Taurate, Magnesium Citrate, Magnesium Aspartate, Magnesium BHB, Magnesium Caprylate), Manganese (as Manganese Citrate), Ionic Trace Mineral Complex. Other Ingredients: Hypromellose (Capsule), Microcrystalline Cellulose, Ascorbyl Palmitate, goMCT® (medium chain triglycerides), gum acacia.

MAGNESIUM BREAKTHROUGH ADVANCED 10 BENEFITS

SUPPORTS HEART HEALTH*

Magnesium contributes to normal cardiovascular physiology, muscle contraction, and blood vessel function. Maintaining healthy magnesium levels supports normal heart function and healthy circulation.*

SUPPORTS A HEALTHY STRESS RESPONSE & RELAXATION*

Healthy magnesium status supports the body’s natural stress response and relaxation pathways. Research suggests combining magnesium with active vitamin B6 may offer additional support for those experiencing everyday stress — which is why Advanced 10 includes P5P, the active form of B6.*

SUPPORTS MOOD, COGNITIVE FUNCTION & MENTAL WELL-BEING*

Magnesium contributes to normal nervous system function and healthy neurological activity. Maintaining healthy levels may support memory, concentration, emotional well-being, and normal neurotransmitter activity.*

SUPPORTS HEALTHY GLUCOSE METABOLISM*

Magnesium is involved in glucose metabolism and normal insulin function. Clinical research suggests adequate magnesium status may help support insulin sensitivity already within the normal range.*

SUPPORTS HEALTHY METABOLIC FUNCTION*

Magnesium is a required cofactor in over 300 enzymatic reactions, including those that convert food into usable cellular energy (ATP). Maintaining healthy magnesium levels supports normal metabolic rate, macronutrient metabolism, and mitochondrial energy production.*

Because energy metabolism runs on magnesium-dependent enzymes, consistent intake is a foundational part of supporting overall metabolic wellness — not just glucose handling alone.*

SUPPORTS EXERCISE PERFORMANCE & RECOVERY*

Magnesium is essential for normal muscle contraction, neuromuscular signaling, and cellular energy production. Maintaining healthy levels may support exercise performance, muscle function, and post-exercise recovery.*

SUPPORTS RESTFUL SLEEP & HEALTHY SLEEP QUALITY*

Magnesium supports normal nervous system function, relaxation, and neuromuscular activity — all part of healthy sleep physiology. Advanced 10 combines 10 forms of magnesium with active B6 (P5P) and ionic trace minerals to support the systems involved in restful sleep, whether you’re winding down at night or maintaining consistent sleep quality over time.*

SUPPORTS BONE HEALTH*

Roughly 50–60% of the body’s magnesium is stored in bone. Magnesium contributes to normal bone formation and supports the body’s utilization of calcium and vitamin D — making it a key part of any bone health strategy.*

SUPPORTS HEALTHY BLOOD PRESSURE ALREADY WITHIN THE NORMAL RANGE*

Magnesium contributes to normal blood vessel function and muscle contraction, helping support blood pressure already within the normal range.*

SUPPORTS HEALTHY IMMUNE FUNCTION*

Magnesium is involved in hundreds of biochemical processes, including those that support immune function, balanced inflammatory response, and overall wellness.*

SUPPORTS VITAMIN D UTILIZATION & METABOLISM*

Magnesium is a required cofactor for enzymes involved in vitamin D metabolism — without adequate magnesium, the body may not utilize vitamin D efficiently. Because high vitamin D intake can increase magnesium demand in some individuals, maintaining adequate magnesium status matters for overall bone, immune, and metabolic health.*

WHY DOES ADVANCED 10 INCLUDE ACTIVE VITAMIN B6 (P5P)?

P5P is the biologically active form of vitamin B6 — it doesn’t require conversion before the body can use it. It’s included to support intracellular magnesium utilization and complement the formula. Research also suggests combining magnesium with B6 may offer added support for those experiencing higher everyday stress, compared with magnesium alone.*

SUPPORTS HEART HEALTH*

Magnesium contributes to normal cardiovascular physiology, muscle contraction, and blood vessel function. Maintaining healthy magnesium levels supports normal heart function and healthy circulation.*

SUPPORTS A HEALTHY STRESS RESPONSE & RELAXATION*

SUPPORTS MOOD, COGNITIVE FUNCTION & MENTAL WELL-BEING*

SUPPORTS HEALTHY GLUCOSE METABOLISM*

Magnesium is involved in glucose metabolism and normal insulin function. Clinical research suggests adequate magnesium status may help support insulin sensitivity already within the normal range.*

SUPPORTS HEALTHY METABOLIC FUNCTION*

Because energy metabolism runs on magnesium-dependent enzymes, consistent intake is a foundational part of supporting overall metabolic wellness — not just glucose handling alone.*

SUPPORTS EXERCISE PERFORMANCE & RECOVERY*

SUPPORTS RESTFUL SLEEP & HEALTHY SLEEP QUALITY*

SUPPORTS BONE HEALTH*

SUPPORTS HEALTHY BLOOD PRESSURE ALREADY WITHIN THE NORMAL RANGE*

Magnesium contributes to normal blood vessel function and muscle contraction, helping support blood pressure already within the normal range.*

SUPPORTS HEALTHY IMMUNE FUNCTION*

Magnesium is involved in hundreds of biochemical processes, including those that support immune function, balanced inflammatory response, and overall wellness.*

SUPPORTS VITAMIN D UTILIZATION & METABOLISM*

WHY DOES ADVANCED 10 INCLUDE ACTIVE VITAMIN B6 (P5P)?

Can I open the capsules and mix them into a beverage?

Yes. Opening the capsules into water, juice, or another beverage doesn’t change how the ingredients are delivered, though it may affect taste. Some people prefer taking it with food for digestive comfort, especially when first starting. Individual tolerance varies.*

What are the benefits of taking Magnesium Breakthrough Advanced 10?

Daily use may help support: healthy magnesium levels, a healthy stress response, restful sleep, muscle function and recovery, healthy nervous system function, cognitive function, cardiovascular health, healthy glucose metabolism, metabolic function, bone health, immune function, and vitamin D utilization.*

How should I take it?

The recommended serving is 550 mg of elemental magnesium (2 capsules) daily, taken consistently. Some prefer it with meals for digestive comfort; others take it on an empty stomach. You can take it in the morning, evening, or split between both — consistency matters more than timing.

What makes Advanced 10 different?

Most magnesium supplements rely on one or two forms. Advanced 10 combines 10 complementary forms because magnesium compounds differ in solubility, dissolution behavior, gastrointestinal tolerance, and bioaccessibility. Every batch is tested for identity, bioaccessibility, and bioavailability.*

Can I take it during pregnancy?

How much magnesium should I take for sleep?

Which form of magnesium is best?

What can contribute to low magnesium levels?

Chronic stress, intense physical activity, aging, magnesium-poor diets, processed foods, excess alcohol, high caffeine intake, certain medications, some digestive conditions, and high vitamin D intake in individuals with low magnesium status.* If you have a medical condition or take prescription medications, consult your healthcare practitioner first.

Which foods naturally contain magnesium?

Is magnesium better than melatonin?

Are there side effects?

Magnesium is generally well tolerated. Some people experience digestive discomfort when starting or increasing intake too quickly — reduce the serving and increase gradually as tolerated. Those with kidney disease or on medications affecting mineral balance should consult their healthcare practitioner first.

Introducing Advanced 10 into your routine

Think of your magnesium reserves like a reservoir — stress, exercise, modern diets, and aging gradually draw it down.* Most people start with the full recommended serving (2 capsules, 550 mg elemental magnesium); others prefer introducing it gradually. Consistency matters more than timing.

Product Information

Product Dimensions

Cap diameter: 1.5 inches
Bottom diameter: 2 inches
Height: 4 inches
Weight: 3.05 ounces

CAUTION:

Use only as directed. Keep out of reach of children. Do not use if safety seal is broken or missing. Consult your healthcare practitioner before use if pregnant, nursing, taking medication, or under medical supervision. Discontinue use if adverse reactions occur.

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Scientific Studies

Brilli, E., et al. "Magnesium bioavailability after administration of sucrosomial® magnesium: results of an ex-vivo study and a comparative, double-blinded, cross-over study in healthy subjects." European Review for Medical & Pharmacological Sciences 22.6 (2018).
Chacko, Sara A et al. "Magnesium supplementation, metabolic markers, and global genomic and proteomic profiling: a randomized, double-blind, controlled, crossover trial in overweight individuals." The American journal of clinical nutrition vol. 93,2 (2011): 463-73. doi:10.3945/ajcn.110.002949 https://doi.org/10.3945/ajcn.110.002949
Dimai, H P et al. "Daily oral magnesium supplementation on bone turnover in young adult males." The Journal of clinical endocrinology and metabolism vol. 83,8 (1998): 2742-8. doi:10.1210/jcem.83.8.5015 https://doi.org/10.1210/jcem.83.8.5015
Golf, S W et al. "On the significance of magnesium in extreme physical stress." Cardiovascular drugs and therapy vol. 12 Suppl 2 (1998): 197-202. doi:10.1023/a:1007708918683 https://doi.org/10.1023/a:1007708918683
Dmitrašinović, Gordana et al. "ACTH, Cortisol and IL-6 Levels in Athletes following Magnesium Supplementation." Journal of medical biochemistry vol. 35,4 375-384. 2 Nov. 2016, doi:10.1515/jomb-2016-0021 https://doi.org/10.1515/jomb-2016-0021
Held, Katja et al. "Oral Mg(2+) supplementation on age-related neuroendocrine and sleep EEG changes in humans." Pharmacopsychiatry vol. 35,4 (2002): 135-43. doi:10.1055/s-2002-33195 https://doi.org/10.1055/s-2002-33195
Human Foods Program. "Qualified Health Claim Magnesium Reduced Risk of High Blood Pressure." U.S. Food and Drug Administration, 2024, https://www.fda.gov/food/hfp-constituent-updates/fda-announces-qualified-health-claim-magnesium-and-reduced-risk-high-blood-pressure. Accessed 9 July 2026.
Joris, Peter J et al. "Long-term magnesium supplementation improves arterial stiffness in overweight adults: results of a randomized, double-blind, placebo-controlled intervention trial." The American journal of clinical nutrition vol. 103,5 (2016): 1260-6. doi:10.3945/ajcn.116.131466 https://doi.org/10.3945/ajcn.116.131466
Kappeler, Dominik, et al. "Higher Bioavailability of Magnesium Citrate as Compared to Magnesium Oxide Shown by Evaluation of Urinary Excretion and Serum Levels after Single-Dose Administration in a Randomized Cross-Over Study." BMC Nutrition, vol. 3, no. 1, Jan. 2017, https://doi.org/10.1186/s40795-016-0121-3.
Numydia Cotry, et al. "Effects of Intuitive Eating Principles and Magnesium Glycinate on Quality of Life, Body Satisfaction, and Stress in Early- and Middle-Aged Adults." TheScholarsRepository@LLU: Digital Archive of Research, Scholarship & Creative Works, 2024, https://scholarsrepository.llu.edu/rr/44/. Accessed 9 July 2026.
Reno, Alyssum M et al. "Effects of Magnesium Supplementation on Muscle Discomfort and Performance." Journal of strength and conditioning research vol. 36,8 (2022): 2198-2203. doi:10.1519/JSC.0000000000003827 https://doi.org/10.1519/JSC.0000000000003827
Schuette, S A et al. "Bioavailability of magnesium diglycinate vs magnesium oxide" JPEN. Journal of parenteral and enteral nutrition vol. 18,5 (1994): 430-5. doi:10.1177/0148607194018005430 https://doi.org/10.1177/0148607194018005430
Schutten, Joëlle C et al. "Long-term magnesium supplementation improves glucocorticoid metabolism: A post-hoc analysis of an intervention trial." Clinical endocrinology vol. 94,2 (2021): 150-157. doi:10.1111/cen.14350 https://doi.org/10.1111/cen.14350
Schuster, Julius et al. "Magnesium Bisglycinate Supplementation in Healthy Adults Reporting Poor Sleep: A Randomized, Placebo-Controlled Trial." Nature and science of sleep vol. 17 2027-2040. 30 Aug. 2025, doi:10.2147/NSS.S524348 https://doi.org/10.2147/NSS.S524348
Setaro, Luciana, et al. "Magnesium Status and the Physical Performance of Volleyball Players: Effects of Magnesium Supplementation." Journal of Sports Sciences, vol. 32, no. 5, Sept. 2013, pp. 438-45, https://doi.org/10.1080/02640414.2013.828847.
Steward, Charles James et al. "One week of magnesium supplementation lowers IL-6, muscle discomfort and increases post-exercise blood glucose in response to downhill running." European journal of applied physiology vol. 119,11-12 (2019): 2617-2627. doi:10.1007/s00421-019-04238-y https://doi.org/10.1007/s00421-019-04238-y
Veronese, Nicola et al. "Effect of oral magnesium supplementation on physical performance in healthy elderly women involved in a weekly exercise program: a randomized controlled trial." The American journal of clinical nutrition vol. 100,3 (2014): 974-81. doi:10.3945/ajcn.113.080168 https://doi.org/10.3945/ajcn.113.080168
Walker, Ann F., et al. "Magnesium supplementation on fluid retention." Journal of women's health 7.9 (1998): 1157-1165.
Walker, Ann F et al. "Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind study." Magnesium research vol. 16,3 (2003): 183-91.
Wienecke, Elmar, and Claudia Nolden. "Langzeit-HRV-Analyse zeigt Stressreduktion durch Magnesiumzufuhr" [Long-term HRV analysis on stress by magnesium intake]. MMW Fortschritte der Medizin vol. 158,Suppl 6 (2016): 12-16. doi:10.1007/s15006-016-9054-7 https://doi.org/10.1007/s15006-016-9054-7
Zogović, Dušanka, et al. "Pituitary-Gonadal, Pituitary-Adrenocortical Hormones and IL-6 Levels Following Long-Term Magnesium Supplementation in Male Students." Journal of Medical Biochemistry, vol. 33, no. 3, July 2014, pp. 291-98, https://doi.org/10.2478/jomb-2014-0016. Accessed 9 July 2026.

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