MAGNESIUM SUPPLEMENT BENEFITS:

SLEEP, STRESS RECOVERY, AND HEALTHY RELAXATION

Get all 7 forms of magnesium for maximum absorption and benefits from this powerful mineral.

  • Support healthy stress response and stress resilience*
  • Promotes heart and metabolic health*
  • A key mineral for healthy immune function*
  • Supports healthy cortisol responses and recovery from stress*
  • A key building block for strong and healthy bones*
  • Promotes calmness and relaxation*
  • Fall asleep faster and get more restful sleep*

Magnesium is an essential mineral. Involved in over 300 biochemical reactions, it plays a vital role in many biological processes, influencing all aspects of health

Most people have been deficient for years, so you’ll likely need a well-absorbed and well-tolerated magnesium supplement. Magnesium Breakthrough was formulated to meet the need for a highly bioavailable magnesium supplement. While most other magnesium supplements use just one, or up to three, types of magnesium, we have combined seven forms alongside other important molecules to maximize absorption. Plus, we deliver these benefits in just two small capsules, providing 500 mg of elemental magnesium per dose! 

The most common side effects people report from taking magnesium supplements are digestive upset and loose stools. Certain forms of magnesium tend to cause these symptoms more than others, especially when products are not well-absorbed which can make the effects worse. By combining magnesium types, many of them known to be more gentle on the stomach, we minimize these effects and enhance absorption.

The combination of magnesium with other compounds helps promote magnesium uptake and use in your body:

  • Pyridoxine HCl: Vitamin B6 acts as a cofactor alongside magnesium for multiple reactions in the body [2]. Both pyridoxine and magnesium have key roles in neurotransmitter synthesis, blood sugar balance, and nerve function [3][1]. So, getting both of these compounds together might help boost their effectiveness. Pyridoxine can also influence magnesium’s transport into cells, increasing cellular uptake [4]. Last but not least, it can also help mitigate how much magnesium is lost through urine to help maintain higher body levels of magnesium [5]. 
  • Humic/Fulvic monoatomic blend: Humic and fulvic acids are organic compounds found in soil and water [6]. They work to help bind and absorb minerals like magnesium and increase their bioavailability, or how well your body can take them up [7]. 

Why 7 Forms of Magnesium Supplement?

Science-Based Health Benefits of Different Types of Magnesium and Their Cofactors in Magnesium Breakthrough.

Magnesium Glycinate[16]

Magnesium Glycinate contains magnesium bound by two glycine molecules. This binding stabilizes the magnesium molecule, allowing for increased absorption in the digestive tract as it can absorb like a two amino acid peptide and bypass the need for stomach acid. As a result, magnesium Glycinate generally has the least gut side effects compared to other formulations, which can be helpful for those with sensitive stomachs. Because glycine is a relaxing amino acid, this form is best for sleep and relaxation.

Magnesium Citrate [11]

Magnesium Citrate combines magnesium with citric acid. This form is one of the most common in magnesium supplements, and has a mild laxative effect, which can make it useful for promoting bowel regularity. It is also an excellent form of magnesium for healthy blood sugar control, blood pressure, and overall metabolic health [12].

MAGNESIUM TAURATE[17]

Magnesium Taurate combines magnesium with the amino acid taurine. The combination can work together to regulate calcium and sodium levels within cells, which may help maintain a healthy blood pressure. Taurine has many roles within the cardiovascular and nervous systems, and this preparation may have additional benefits in supporting heart and brain health.

MAGNESIUM CHELATE [10]

Magnesium Chelate consists of magnesium that is bound to a chelating agent, such as amino acids. In Magnesium Breakthrough, it’s chelated with rice flour. This binding helps to enhance transportation across the intestinal wall and into the blood, improving bioavailability. This form is generally mild on the gut compared to other preparations, and may be less likely to interfere with the absorption of other minerals.

MAGNESIUM OROTATE

Magnesium Orotate consists of magnesium bound to orotic acid. This preparation is believed to have more affinity for the cardiovascular system. Orotic acid is also involved in DNA and RNA synthesis, and can act as an antioxidant.

MAGNESIUM MALATE [14] 

Magnesium Malate combines magnesium with malic acid, which is a compound that occurs naturally in fruits and vegetables. This combination provides synergistic effects (greater than the sum of its parts) in the body. Both magnesium and malic acid are involved in specific brain processes, which may increase their individual benefits when combined.

SUCROSOMIAL® MAGNESIUM [15] 

Sucrosomial® Magnesium uses a specialized delivery system in order to increase the amount of magnesium that is absorbed through your gut and into your red blood cells. Magnesium is encapsulated in a structure of sucrose esters, which create a barrier through the digestive tract and allow for it to cross into the blood without interacting with the digestive tract lining. In a small clinical study, Sucrosomial® magnesium increased red blood cell magnesium better than magnesium glycinate and oxide.

Cofactors in Magnesium Breakthrough

Vitamin B6[18], also known as pyridoxine, is important for many enzymatic reactions in the body, including ones related to protein metabolism, synthesis of neurotransmitters, and energy production. A few clinical trials have demonstrated that vitamin B6 enhances the mood and stress resilience benefits of magnesium.

Humic/Fulvic Monoatomic Blend [19]: Humic and fulvic acid interact with both magnesium and vitamin B6 to support their absorption and utilization in the body. They have chelating properties that enhance the solubility and uptake of magnesium, which may increase the amount of magnesium available to various tissues.

Manganese Citrate[20]: Manganese is a key micromineral that functions as a cofactor for many biological processes in the body. The small amount of manganese in Magnesium Breakthrough helps balance the magnesium and may also improve sleep. Clinical evidence suggests a manganese imbalance can lead to suboptimal sleep.

SYNERGISTIC EFFECTS OF
MAGNESIUM BREAKTHROUGH INGREDIENTS

Magnesium Breakthrough has a unique cutting-edge formulation, with all of the ingredients working together in synergy to deliver its benefits. Some examples of how these compounds work together include:

  • Synergistic effects on stress resilience[21]: Taking magnesium in combination with pyridoxine improves stress levels more effectively than magnesium alone. 
  • Absorption and bioavailability[22]: Humic and fulvic acid can enhance the solubility and bioavailability of magnesium, supporting how well it is taken up and utilized by the body. 
  • Neurotransmitter synthesis[21][23]: Both B6 and magnesium are important for the synthesis of neurotransmitters in the brain. For example, vitamin B6 is needed for converting the amino acid tryptophan into serotonin (a neurotransmitter that regulates mood), while magnesium is needed for the conversion of amino acid tryptophan into serotonin and melatonin (a hormone that regulates the sleep-wake cycle). 
  • Heart health[24][25][26]: Vitamin B6 and fulvic acid helps to regulate levels of homocysteine, an amino acid that affects heart health when high. Magnesium helps to support normal heart rhythm, maintain blood pressures already within a healthy range, and support overall cardiovascular function.  
  • Electrolyte balance [27]: Magnesium is an essential electrolyte in the body, and both humic and fulvic acid may help to maintain proper magnesium balance by supporting the absorption, distribution, and retention of magnesium.  

Magnesium Breakthrough is a proprietary blend because the formulation is unique and expertly formulated and tested to maximize its effectiveness. Therefore, it is an intellectual property that we cannot disclose to the public.

The Epidemic of
Magnesium Deficiency

Serum Magnesium Level May Not
Diagnose Low Magnesium

Serum magnesium level can be normal or high even with a frank magnesium deficiency.[30]

Magnesium is an electrolyte mineral, which means that too high or too low serum levels can cause life-threatening changes in heart and lung functions, or lead to shock. Therefore, the body will do everything possible to maintain serum magnesium within the normal levels. This means your serum magnesium can look normal even though there is a magnesium deficiency [31]. These compensatory mechanisms can supplement serum magnesium levels but cause a “cellular” magnesium deficiency. This means that within the cell, there is not enough magnesium despite serum levels within normal ranges.

Magnesium Breakthrough Health Benefits

Magnesium is an example of an essential mineral. This means that it is vital for the proper functioning of the body. Essential minerals cannot be made by the body, unlike some vitamins, and therefore must be obtained from outside sources.

Some benefits associated with magnesium include:

  • Supporting enzyme activity[31]: Magnesium is involved in hundreds of enzyme reactions in the body, which are important for energy production and metabolism.
  • Energy production[31]: Magnesium helps to convert food into energy that can be used by the body, and adequate magnesium levels play a role in supporting optimal energy levels and reducing fatigue.
  • Muscle function[34]: Muscles require magnesium in order to function properly. It helps to regulate muscle contraction and relaxation, and can be helpful for reducing muscle cramps, and spasms, and promoting overall muscle health.
  • Bone health[35]: Magnesium works with other minerals, including calcium and vitamin D, to support bone health. Heart health[36]: Magnesium supports the cardiovascular system by promoting healthy heart rhythm and blood vessel function.
  • Blood sugar regulation[37]: Magnesium is involved in insulin metabolism, and helps to maintain healthy blood sugar levels.
  • Sleep[38]: Magnesium can help regulate melatonin production, a hormone involved in the sleep cycle, which may promote healthy sleep.

Individual requirements for magnesium vary, and specific health benefits can depend on many different factors, including your age, health status, and any underlying conditions. Therefore it is always recommended to consult with a healthcare provider prior to beginning supplementation to address any specific health concerns and ensure that it is appropriate for you.

HERE’S WHY MAGNESIUM BREAKTHROUGH IS PARTICULARLY BENEFICIAL.

HEALTHY STRESS RESPONSE AND STRESS RESILIENCE

Supports Healthy GABA Levels and Functions [39][29]

Supports Healthy Cortisol Response and Breakdown[29][41][42]

Replenish Lost Magnesium During Stress[41][43][44][45]

HEART HEALTH AND HEALTHY HEART RHYTHM[45][36][47][41]

WOMEN'S HEALTH

Healthy Menstrual Cycles and Fertility

Menopause Well-being

Bone Health

ATHLETIC PERFORMANCE AND TRAINING RECOVER

MEN'S HEALTH

ARE ALL MAGNESIUM SUPPLEMENTS THE SAME?

Unfortunately, cheap magnesium supplements can be poorly absorbed and harsh on the gut. So, you could be getting less than 10% of what you pay for with these. Take more and it could send you straight to the bathroom.

Also, the more expensive forms of magnesium like glycinate and malate are actually ~14 - 20% elemental magnesium in weight. The remaining 80 - 86% of the weight are glycine and malate, respectively. If the label reports only 100 - 200 mg total ingredient per capsule, you’d need to take 10 - 20 capsules to get your recommended daily intake dose.

Magnesium Breakthrough contains 7 forms of magnesium that clinical studies have shown to be well absorbed. Also, each capsule contains 250 mg of elemental magnesium (not total ingredient weight). That means only 2 capsules exceed the recommended daily intake dose.

Many of our customers take more than 2 capsules, in the beginning, to correct long-term deficiencies and optimize their body’s magnesium levels.

The Best Magnesium Supplement For You and Your Family

WHAT ARE SOME MAGNESIUM DEFICIENCY SYMPTOMS?

Magnesium deficiency can manifest in many different ways, and many of the symptoms associated with magnesium deficiency can overlap with other conditions. Some of the most common symptoms related to magnesium deficiency include [73]:

WHAT CAUSES MAGNESIUM DEFICIENCY?

Multiple factors may contribute to magnesium deficiency, including underlying disorders, individual susceptibility, and lifestyle factors. Some common causes of magnesium deficiency include:

  • Insufficient dietary intake [75]: A diet that lacks magnesium-rich foods can cause magnesium deficiency. Foods that are rich in magnesium include green leafy vegetables, nuts and seeds, legumes, whole grains, and some seafood. A lack of magnesium-rich foods in the diet can contribute to inadequate dietary intake and cause magnesium deficiency.
  • Poor absorption [75]: Poor gut health or suboptimal stomach acid can impair magnesium absorption from the diet and may contribute to magnesium deficiency.
  • Excess kidney excretion [75]: The kidneys help maintain mineral balance, so when the kidney excretes too much magnesium, it can lead to a deficiency.
  • Aging [74]: The body’s ability to absorb and utilize magnesium may decline with age, increasing the risk of magnesium deficiency in older adults. Appetite changes or dietary limitations that may occur with aging may also impact intake levels.
  • Chronic stress [29]: High stress levels can increase the release of stress hormones, such as cortisol, which can increase the urinary excretion of magnesium and reduce levels in the body.
  • Pregnancy and lactation [74]: Magnesium requirements increase during pregnancy and lactation, to support fetal development and breast milk production. If dietary intake is insufficient to account for this increased demand, magnesium deficiency can occur.
  • Alcohol intake [74]: Alcohol can impair the body’s ability to retain magnesium, and excessive intake of alcohol can impact both magnesium absorption and increase urinary excretion, contributing to magnesium deficiency.
  • Medications [76][74]: Medications that can increase urinary excretion of magnesium or interfere with its absorption include diuretics (water pills), proton pump inhibitors (PPIs), some antibiotics, and others used in the management of diabetes and high blood pressure.

If you suspect magnesium deficiency, it's important to consult with a healthcare professional for proper evaluation, diagnosis, and appropriate treatment or supplementation.

WHAT ARE BIOPTIMIZERS
MAGNESIUM BREAKTHROUGH SIDE EFFECTS?

Magnesium is generally safe for most people when consumed within the recommended dosages. Excessive intake of magnesium may cause side effects in some individuals, including [76]:

WHERE TO BUY MAGNESIUM BREAKTHROUGH?

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  • Advanced magnesium to support sleep*
  • Promotes a calm, balanced stress response*
  • Supports more restful sleep*
  • Supports everyday immune health*
  • Provides an essential electrolyte for cellular balance*
  • Provides a foundational mineral for bone health*
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  • Best magnesium supplements to support sleep*
  • Promotes a balanced stress response to feel relaxed and at peace*
  • May improve sleep quality*
  • A key nutrient that may assist in a healthy immune response*
  • Provides an essential electrolyte to maintain a healthy heart function*
  • Provides a key mineral building block to strong bones*
  • Contains 8 different forms of magnesium
  • Organic, natural flavors and colors
  • Sweetened with Katemfe fruit extract: a protein that is 3,000 times sweeter than sucrose (does not spike glucose when metabolized)
  • Vegetarian powder

REFERENCES