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Support for Healthy Digestion, Metabolism, and Sleep —
All in One Routine

Black Friday Cyber Monday BIOptimizers
33% off Masszymes bottle
349 Reviews

MassZymes

Capsules

Helps break down protein, fat, and carbs for smoother digestion and better nutrient absorption.*

$26.80
$40.00
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33% off Probiotic Breakthrough bottle
240 Reviews

Probiotic Breakthrough

Capsules

Supports gut balance and immune function during colder, indulgent months.*

$26.80
$40.00
Click to Learn More
Black Friday Cyber Monday BIOptimizers
33% off Berberine Breakthrough bottle
48 Reviews

Berberine Breakthrough

Capsules

Supports healthy glucose metabolism and supports steady energy levels daily.*

$40.20
$60.00
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33% off Sleep Breakthrough bottle
52 Reviews

Sleep Breakthrough

Capsules

Promotes relaxation and deeper sleep so your body can fully recharge overnight.*

$26.80
$40.00
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33% off cognibiotics bottle
52 Reviews

Sleep Breakthrough

Powdered Drinks

Mixable drink promotes relaxation and deeper sleep for your body's full recharge.*

$43.55
$65.00
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Black Friday Cyber Monday BIOptimizers
25% off Magnesium Breakthrough bottle
1550 Reviews

Magnesium Breakthrough

Capsules

7 forms of magnesium for full-spectrum sleep support, deep calm, and restorative rest.*

$30.00
$40.00
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25% off cognibiotics bottle
8 Reviews

Magnesium Breakthrough

Powdered Drink

8 forms of magnesium in a soothing drink to help you relax, unwind, and prepare for restful sleep.*

$30.00
$40.00
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Recommended by Top Health Experts & Performers

Dr Leaf

Ben Greenfield

I rely on BIOptimizers’ expertly crafted formulas for digestion, energy, brain function, and restful sleep—they're a staple in my daily routine.

Chalene Johnson

Chalene Johnson

Magnesium is essential for everything—sleep, energy, hormones, and more. Magnesium Breakthrough gives me all the types I need in one formula. Take this daily!

Dr Mark Hyman

Dr Mark Hyman

Magnesium Breakthrough has the full spectrum of magnesium, which can dramatically improve your overall health, from reducing stress to improving sleep and boosting energy

Dr Leaf

Dr. Leaf

As a neuroscientist, I know how important sleep is. But I also know how hard it can be to get enough sleep! This is why I love Magnesium Breakthrough.

Dr Leaf

Dave Asprey

You’re not just what you eat – you're what you absorb. And most people aren’t absorbing their food. That’s where MassZymes by BIOptimizers helps. Take them with food to help you make the most out of every meal.

Dr Leaf

Dr. Tyna Moore

MassZymes by BIOptimizers is my favorite digestive enzyme. It has made a significant difference for me, and I recommend it to all my patients. One of the reasons I love it is its high protease content, which helps effectively digest protein. I encourage you to give MassZymes a try.

Dr Leaf

Dr. Robert Love

I love MassZymes by BIOptimizers. It improves my digestion and energy, and decreases bloating after a big meal. If you want to feel better after eating, and get more nutrition from your food, try MassZymes

Dr Leaf

Sal Di Stefano (Mind Pump)

Taking MassZymes with my high protein meals significantly helps with digestion. I feel lighter digestively speaking post meal.

The 365 Day "Best Product Ever Or Your Money Back" Guarantee

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The 365 Day "Best Product Ever Or Your Money Back" Guarantee

All BIOptimizers products come with a 365-Day Money Back Guarantee. If you are not completely satisfied with your BIOptimizers product for any reason between today and 365 days from now, just send back your remaining unopened bottles of the product and we'll give you a full refund (minus the cost of shipping and handling). If you open a second bottle, you no longer qualify for any guarantee. Reach out to our customer happiness team and they will take complete care of it.