The following supplements can help with fat digestion:

• Bitters such as dandelion root
• Bile salt supplement, although these only come from animal sources
• Plant-based emulsifier, such as lecithin
• Lipases, or fat-digesting enzymess

AMPK (AMP-activated protein kinase) is an energy sensor11 inside your cells. When energy (ATP) levels are low, AMPK kicks in to increase fat burning, stimulate your mitochondria, promotes cellular self-cleanup, and increases insulin sensitivity.

Ways to increase AMPK naturally include:

1. Exercise^[12]
2. Fasting and caloric restriction^[13]
3. Ketogenic diets^[14]
4. Managing inflammation^[15]
5. Cold exposure^[16]
6. Taking specific extracts of Notoginseng and astragalus, such as in Innoslim

Does AMPK help lose weight?

It depends on where. Activating AMPK can stimulate^[17] your mitochondria, increasing fat burning and helping with weight loss. However, activating AMPK in the hypothalamus^[18] in your brain^[19] can increase appetite. The pathways activated by Innoslim mainly work inside fat and muscle cells.

AMPK is a natural substance found in all cells of your body. It is possible that activating it too much can lead to side effects. For example, AMPK participates in some pathways that prevent neurodegenerative diseases and cancers, but also play some roles in pathways that promote these diseases. Drugs that stimulate AMPK, such as metformin and salicylates have their own side effects. Whereas, Innoslim does not have the same side effects as these drugs.

The liver is a metabolically active organ. It takes a lot of energy to metabolize all the toxins in the body into forms that can be safely eliminated. The liver is also responsible for producing bile, which helps digest fat, and burning fat into ketones.

• Poor digestion and constipation
• Inability to lose weight
• Hormone imbalances
• Fatigue
• Skin breakouts
• High cholesterol
• Inability to tolerate alcohol or chemical exposure
• Headache

The term “Paleo Diet” is a dietary philosophy based on the archaeological principles of the foods that were available to hunter-gatherers. It advocates for the omission of grains, legumes, sugar, processed foods, and dairy, which often by default causes the diet to become low-carb. However, the Paleo diet is a broad descriptor that can include anywhere between a carnivore (no plant) diet to a mostly plant diet with sprinkles of animal products.

Some aspects of Paleo could be good for gut health. These include the avoidance of grain-fed animal products that are high in pesticides and antibiotics. Paleo also advocates high-antioxidant and high-fiber vegetables and fermented foods, which are good for the gut bacteria.

For some people who are sensitive to lectins, gluten, other plant anti-nutrients, and dairy, eliminating grains and legumes often heal their gut. However, grains and legumes are also great sources of resistant starch for people who are not sensitive to these foods. There are some concerns that people who are on low or very low-carb Paleo versions could be starving their gut bacteria. Whether the Paleo diet is good or bad for the gut depends on whether the diet is compatible with their physiology.

Many people transition into a Paleo diet by just removing the grain-containing foods, which leaves them only between 50 - 100 grams of carbs, including vegetables. In these cases, they may be on a low carbohydrate diet, which can cause similar side effects as keto adaptation, including:

• Carbohydrate cravings
• Fatigue, brain fog, and irritability
• Digestive symptoms
• Bad breath

Both Paleo and Keto diets are significant upgrades compared to the Standard American Diet. These two terms are different, although not mutually exclusive.

The Paleo diet recommends low-toxin and nutrient-dense foods, which are ideally organic and local. The food should also be grown according to its natural conditions, such as grass-fed cattle, wild-caught fish, and free-range eggs. The diet recommends plenty of fresh vegetables, fruits, nuts and seeds, high-quality meats, eggs, fish and seafood, and spices. Natural monounsaturated and nutrient-dense saturated fats, such as olive oil, avocados, tallow, lard, mct oil, coconut oil and coconut are recommended. Whereas, grains, legumes, vegetable oils, dairy, sugar, artificial sweeteners, and processed foods are recommended against.

The diet doesn’t specify a macronutrient composition, but rather leave it to the individual to decide what works best for them. Most Paleo eaters follow a low to moderate carbohydrate version, which is much less than what most Americans consume in a Standard American Diet. However, some athletes add a lot more fruits and tubers to support their training, while some Paleo eaters deliberately increase the fats to make it ketogenic.

The ketogenic diet refers to any diet that is very high in fat and very low in carbohydrates, with a goal of entering ketosis. The food does not have to be natural, organic, or local. Some keto diet followers consume a lot of dairy and even vegetable oils, whereas others stick to natural and nutrient-dense foods.

The ketogenic diet, or the presence of ketone bodies in the blood, have some medicinal potential that the paleo diet doesn’t. For example, it can help manage treatment-resistant epilepsy. Also, many clinical studies are ongoing to evaluate other potential medicinal properties of ketogenic diet. If you are working with your doctor to manage a health condition with a ketogenic diet, then the ketogenic diet might be healthier for you. In such cases, you need to speak to your doctor before introducing any keto diet supplements.

We advocate for nutrient-dense, whole, and natural foods, when possible. Also, we recommend choosing the diet that works best for you based on how you feel and your health markers after the initial adaptation period. Neither diet is suitable for everyone, but kApex® can help make the adaptation period easier.

Adiponectin is a small protein hormone produced by fat cells. It helps reduce inflammation, increase burning fat, promotes insulin sensitivity, and promotes heart and blood vessel health.

• Consuming enough omega-3
• Consuming less carbohydrates
• Consuming more monounsaturated fats, such as olive oil, avocados, and macadamia
• Consuming fiber may increase adiponectin by 60 - 115%
• Exercise
• Cold thermogenesis
• Using kApex®

Glut4 is a glucose transporter in fat and muscle cells. It brings glucose into the cells once triggered by insulin. When someone is insulin resistant, it’s because they have a problem with Glut4, such as lacking glut4 on the cell surface or that glut4 doesn’t function correctly.

• Exercise
• Consuming less carbohydrates
• Caloric restriction and fasting
• Vitamin D
• How can I lower my LDL cholesterol naturally?
• Lowering saturated fat intake and replace it with monounsaturated fats instead
• Consuming more fiber
• Optimizing your gut health and microbiome, as high bacterial toxin in the blood due to leaky gut can increase LDL cholesterol. Leaky Gut Guardian promotes a healthy gut barrier and binds up some bacterial toxins.
• Restoring insulin sensitivity reduces the more dangerous (small and dense) LDL
• Can you increase the number of mitochondria in your body?
• Exercise
• Ketogenic diet
• Caloric restriction/fasting
• Cold exposure
• Dietary antioxidants in fruits and vegetables