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  • Best magnesium supplements for sleep
  • Promotes a balanced stress response to feel relaxed and at peace
  • Sleep faster and deeper
  • A key nutrient for healthy immune responses
  • Provides an essential electrolyte to maintain a healthy heart rhythm
  • Provides a key mineral building block to strong bones
  • Contains 8 different forms of magnesium
  • Organic, natural flavors and colors
  • Sweetened with Katemfe fruit extract: a protein that is 3,000 times sweeter than sucrose (does not spike glucose when metabolized)
  • Vegetarian powder

MAGNESIUM BREAKTHROUGH DRINK - 30 servings

MAGNESIUM BREAKTHROUGH DRINK - 30 servings

MAGNESIUM BREAKTHROUGH DRINK - 30 servings

Magnesium Plus Magnesium Vitamin Cofactors Now Available In A Powder

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Due to high demand, we recently ran out of Magnesium Breakthrough but we are back in FULL STOCK. Be aware, due to extreme demand it can take 3-5 days to ship it out. We appreciate your patience and understanding.

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  • Best magnesium supplements for sleep
  • Promotes a balanced stress response to feel relaxed and at peace
  • Sleep faster and deeper
  • A key nutrient for healthy immune responses
  • Provides an essential electrolyte to maintain a healthy heart rhythm
  • Provides a key mineral building block to strong bones
  • Contains 8 different forms of magnesium
  • Organic, natural flavors and colors
  • Sweetened with Katemfe fruit extract: a protein that is 3,000 times sweeter than sucrose (does not spike glucose when metabolized)
  • Vegetarian powder
Frequently Bought Together

Why Getting ALL 8 Forms of Magnesium Transforms Your Stress & Performance

One of the biggest misconceptions about magnesium is that you just “need more” of it and you’ll be healthy and optimized.

But the TRUTH is, there are many different types of magnesium — and each plays a critical role in different functions in your body.

Most “healthy” people only get 1-2 forms at best (much of the population is deficient in all forms) — but when you get all 8 major forms of magnesium, that’s when the magic happens.

Magnesium Chelate

This form of magnesium is especially important for muscle building, recovery, and health.

Magnesium Citrate

This form of magnesium supports metabolic health. In fact, one study found that this form may improve blood vessel health in healthy overweight individuals.

Magnesium Bisglycinate

This is the best form of magnesium for muscle and overall relaxation responses.

Magnesium Malate

Some believe this to be the most bioavailable form of magnesium. It’s found naturally in fruits, giving them their tart taste.

Magnesium Sucrosomial

This form of magnesium is very well absorbed. It helps you to effectively produce energy. It also supports the immune system and bone health.

Magnesium Carbonate

This alkaline form of magnesium provides a delicious fizz in the magnesium drink. It also helps with exercise performance and recovery, pH balance regulation, and overall well-being.

Magnesium Taurate

This is the form of magnesium that is best for your heart.

One study noted: “The complex magnesium taurate may thus have considerable potential as a vascular-protective nutritional supplement.”

Magnesium Orotate

While also helpful for the heart, magnesium orotate is believed to be the best form for metabolic improvements.

This makes it a favorite for athletes seeking enhanced recovery, energy, and performance.

Getting ALL of these forms of magnesium, in the optimum dose, upgrades virtually every function in your body.

Ingredients BiOptimizers Magnesium Breakthrough Strength Sensei Quadra Mag Livewell Magwell Zeal Naturals Magnesium Natural Rhythm Triple Calm Magnesium BioEmblem Triple Magnesium Complex Terranics Magnesium Complex Life Extension Magnesium Caps
Glycinate
Taurate
Orotate
Sucrosomial
Carbonate
Citrate
Chelate
Malate

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Get Your Magnesium Level To The Optimal Zone

Get Your Magnesium Level To The Optimal Zone

Why Magnesium Breakthrough:

Magnesium is one of the most important minerals for all aspects of health. It participates in over 600 different biochemical reactions in your body. Yet, over 80% of the population doesn’t get the minimum amounts of the types of magnesium they need from diet alone because US soil lacks it. Magnesium deficiency affects all aspects of health. It can also contribute to many aspects of suboptimal health and metabolism, and accelerated aging.

Even people who supplement tend to take types that are poorly absorbed, or they only take two types of magnesium at most. Each type benefits different tissues and organ systems. If you’re only taking one or two forms, you’re most likely still deficient.

BIOptimizers Magnesium Breakthrough is the only supplement on the market that offers the full spectrum of all eight types of magnesium specially formulated to reach every tissue in your body to provide maximum health benefits and reverse low levels that could be contributing to suboptimal health.

Promotes Healthy Stress and Relaxation Responses

Magnesium is extremely important for mental and neurological health. In humans, a low-magnesium diet is associated with poor mood and unhealthy stress responses. You need magnesium to deal with stress, such as to recover your hormones to non-stress levels so you can rest and relax. Stress causes you to excrete more magnesium through urine. Therefore, being deficient can create a vicious cycle.

Magnesium supplementation has been shown to promote a healthy stress response and neurotransmitter balance. It also promotes relaxation by increasing GABA, the calming neurotransmitter.

Magnesium supplements have also been shown to help improve mental health in women with general premenstrual syndrome.

To boost mood and promote a healthy stress response, it is best to use a combination of forms of magnesium combined with vitamin B6. Studies have confirmed that magnesium with organic acid salt (e.g. citrate and malate) or amino acids (e.g. taurate, glycinate, and sucrosomial) are significantly better absorbed than inorganic salts (oxide, chloride, and sulfate). Also, these different forms are absorbed into different tissues, with taurate, malate, and citrate being the most beneficial for the nervous system.

BIOptimizers Magnesium Breakthrough contains the full spectrum of all eight forms of the most bioavailable magnesium along with vitamin B6 to support mental health and promote a healthy stress response.


INGREDIENTS:

Magnesium Chelate, Magnesium Carbonate, Magnesium Bisglycinate, Sucrosomial Magnesium, Magnesium Malate, Magnesium Taurate, Magnesium Orotate, and Magnesium Citrate.

MANY OF PRODUCTS ARE:

Dairy Free
Dairy
Free
Gluten Free
Gluten
Free
Vegan
Vegan
Sugar free
Sugar
Free
Chemicals & Fillers Free
Chemicals &
Fillers Free
Natural Ingredients
All Natural
Ingredients
USA made
USA made with
globally-sourced
ingredients

Magnesium Breakthrough Benefits

  1. Promotes Heart Health

    Magnesium is extremely important for heart health and blood vessel health. Correcting deficiency appears to improve heart health and reduce the risk of death, although it is unclear whether supplementation alone is sufficient to treat these conditions.

  2. Improves the Ability to Deal With Stress and Helps to Relax

    A magnesium supplement significantly reduces stress perception in people who are deficient in magnesium. Also, combined with vitamin B6 it was 40% more helpful than alone in very stressful situations. Findings support the need for magnesium supplementation for people living in conditions of chronic stress.

  3. Helps With Mood, Cognitive Function, and Mental Health

    A clinical trial showed that a magnesium supplement significantly improved mood after 2 weeks. Another trial found that magnesium supplements improved mood in seniors.

  4. Promotes Healthy Blood Sugar Control Already within Normal Range And Promotes Healthy Metabolism

    You need magnesium to provide healthy levels of insulin. Then, insulin needs magnesium to deliver signals to your cells. Once sugar is inside your cells, you need magnesium to effectively burn the sugar for energy.

    Magnesium is important for hormones that regulate blood sugar to function well. Therefore, a magnesium deficiency can contribute to suboptimal blood sugar control. Even when the blood sugar is normal, a supplement would still be necessary to achieve optimal levels.

    Magnesium participates in many biochemical reactions involved in breaking down stored fat and food for energy. So, a lack of magnesium can make your metabolism less efficient and you may find it harder to lose weight.

    A large-scale systematic and dose-response analysis found that magnesium supplementation seemed to help with weight loss, especially in the midsection. Women and those with suboptimal blood sugar control seemed to reap more weight loss benefits from magnesium. Participants seemed to weigh less and had smaller waist circumference if they took magnesium supplements.

    The drop in waistline was small (less than an inch for an obese person) but statistically significant in this study, suggesting that it could be even more powerful when combined with deliberate caloric deficit and exercise.

    Magnesium on its own doesn’t solve blood sugar problems or cause weight loss, but it can be highly beneficial in combination with diet and exercise.

  5. Supports Exercise Performance and Recovery

    Magnesium supplementation improves speed and strength, possibly by making glucose metabolism more efficient. It also supports healthy stress response to exercise, counteracts excessive muscle damage, and improves exercise recovery (400 mg/day, taken at breakfast).

  6. Improves Sleep Quality

    In a small clinical trial involving 46 elderly subjects with sleep struggles, 500 mg of daily magnesium supplement improved sleep quality, sleep latency, and cortisol. Subjects also had more serum melatonin, slept deeper, and were less likely to wake up in the middle of the night.

  7. Builds Stronger Bones

    Magnesium is the key building block of your bones. Magnesium deficiency can weaken your bones by:

    • Inhibiting healthy bone formation, creating brittle bones
    • Increasing cortisol, which can contribute to lifestyle-related gradual bone loss
    • Reducing parathyroid hormone
  8. Promotes Healthy Blood Pressure

    A meta-analysis of 34 randomized control trials found that magnesium reduced blood pressure. However, the effect size is clinically small (<2 mmHg). Therefore, it may be good for supporting overall health and healthy blood pressure, but you may also need other interventions to achieve healthy blood pressure levels.

  9. Promotes Balanced and Healthy Immune System

    Magnesium is a crucial mineral for your immune system and activates Vitamin D, another key nutrient for healthy immune functions and balance.

    Overall, magnesium deficiencies tend to exacerbate or increase the risk of conditions that involve chronic inflammation.

  10. Supports Vitamin D Activation and Metabolism

    Both Vitamin D and magnesium have important roles in bone health, immune function, and metabolism. Magnesium is a cofactor in Vitamin D conversion and activation. Some people cannot increase their blood 25-hydroxy Vitamin D levels despite supplementing with Vitamin D3 because they are deficient in magnesium. In other words, magnesium deficiency can make Vitamin D less effective.

    Also, in people deficient in magnesium, high doses of Vitamin D3 could worsen magnesium deficiency and increase the potential for side effects of excessive Vitamin D3, such as having excess calcium.

How To Take Magnesium

When you take magnesium in the morning, it supports brain function and stress response throughout the day. In the evening, high doses of magnesium promote relaxation and may help with sleep. Therefore, it is best to divide your magnesium supplement doses throughout the day. If that is not possible, take it whenever you can.

It is better to take mineral supplements, such as magnesium, on an empty stomach because you will absorb it more efficiently. However, some people experience upset stomach, so they take it with food.

Studies of inorganic magnesium salts (oxide, chloride, and sulfate) found that stomach acid is necessary for magnesium absorption, so it needs to be taken on an empty stomach. However, organic magnesium salts (citrate, glycinate, chelate, etc.) are more readily absorbed even when taken with food.

Our bodies don’t store magnesium well. It is generally excreted from your system within 24 hours of intake. Therefore, it is important to take magnesium every day.

Magnesium Breakthrough
Ultimate Sleep System
How To Reduce Stress
Social Situations

Magnesium Breakthrough Questions:

What is the B6 in Magnesium Breakthrough made from?

Vitamin B6 improves magnesium absorption and bioavailability. A clinical study compared the effects of magnesium with magnesium combined with B6. They found that subjects who were going through a lot of stress experienced a 24% greater reduction in stress scores with magnesium and Vitamin B6 compared with magnesium alone. The Vitamin B6 in this product is made from carbohydrate fermentation (not potato starch).

What are the benefits of taking Magnesium Breakthrough?
  • 8 types of magnesium make it the most complete blend available
  • Promotes a healthy stress response
  • Improves sleep quality
  • Supports brain function, memory, and cognitive function
  • Helps muscle building and recovery
  • Boosts exercise performance for athletes, the elderly, and people with suboptimal health
  • Improves mood and mental health
  • Improves blood sugar control in people with normal blood levels
  • May relieve some PMS symptoms and promote hormonal well-being in women
Is this product safe for children?

Consult with your pediatrician. The recommended daily allowance of magnesium for children 9-12 is 240 mg/day which is lower than a scoop of this Magnesium Breakthrough®. If your pediatrician approves, you may want to start with half or ⅔ of a scoop.

How do you take magnesium?

Magnesium Breakthrough is best taken on an empty stomach for best absorption. If you get an upset stomach taking it without food, you may want to take it with some food. A scoop of Magnesium Breakthrough Drink has 325 mg, which can help you reach or exceed the recommended daily intake of magnesium in combination with the magnesium you normally get from food.

For maximum relaxation and cognitive and physical performance, some people experience even more benefits when they gradually step their doses up to 5000 mg/day, broken into a few doses. Our bodies are intelligent and can tell how much magnesium you need if you continue to experience improved relaxation and well-being. You can take it at any time that works best for you. Taking it in the morning can boost mood by promoting calmness throughout the day. However, many people take it at night to relax before bed and promote more restful deep sleep.

What is the best magnesium supplement?

Not all magnesium supplements are created equal due to the differences in bioavailability.

Bioavailability correlates with health benefits. If the magnesium doesn’t reach your target tissue, you won’t reap the benefits from it.

Magnesium Breakthrough® provides the most bioavailable combination of different forms of magnesium on the market.

Can you take magnesium when pregnant?

Please note that Magnesium Breakthrough is not formulated or tested for pregnant women. Katemfe is not tested in pregnant women. It’s best to consult your OB/GYN before introducing any supplements during pregnancy.

For pregnant women, the National Institute of Health recommends a daily magnesium intake of 360 - 400 mg (slightly above the recommended amount for non-pregnant women over the age of 25). This is in part because hormonal changes during pregnancy cause more magnesium to be excreted through the urine.

How many servings per jar?

30 servings per jar.

Frequently Asked Questions:

When do you take magnesium for sleep?

To support sleep, take on an empty stomach 1 - 2 hours before bedtime.

How much magnesium should I take for sleep?

It depends on how deficient you are and your individual magnesium needs. If you’re under more physical or emotional stress, you may need more than an average person. Physical stressors include exercise and physical jobs. Vitamin D supplementation (which also helps with sleep) may also increase magnesium needs.

The recommended daily allowance for magnesium is ~400 mg/day for men and ~310 mg/day for women. However, very few people get this dose from food. If you haven’t taken magnesium for a long time and are deficient, taking the RDA dose can be like filling up an empty pool with a spoon. Therefore, it may be a good idea to start at a higher than the RDA dose to correct the deficiency faster.

Studies have shown the benefits of magnesium supplementation from 125 mg to 2500 mg/day. You want to start with 1-2 scoops, then slowly increase the dosage and observe your body’s response. If you have kidney problems or are on medications that may affect mineral balance (e.g. hypertension medication), it is important to speak to your physician before introducing a magnesium supplement.

Which magnesium is best for relaxation and sleep?

Magnesium chelate, glycinate, citrate, and malate can promote relaxation and sleep. Magnesium Breakthrough contains all of these forms of magnesium.

What can make you deficient in magnesium?
  • Mental/emotional stress
  • Hard physical exertions
  • Caffeine intake
  • Suboptimal blood sugar control or extra weight
  • High doses of Vitamin D supplementation
  • Calcium and other mineral supplements
  • An unhealthy diet with a lot of processed foods
  • Alcoholism
  • Stomach acid-reducing drugs
  • Old age
  • Gut issues that affect magnesium absorption
  • Some medications

If you have a medical condition or are taking medications, consult your physician before introducing any supplements or getting off the medications.

What foods are high in magnesium?

These foods could be high in magnesium if they’re grown in soil that contains it. However, due to modern agricultural practices, most soils are low in magnesium. Plant-based magnesium also tends to come with antinutrients that bind magnesium.

  • Green leafy vegetables
  • Dark chocolate
  • Avocado
  • Nuts and seeds
Is magnesium better for sleep than melatonin?

Magnesium does different things than melatonin. Melatonin is a nighttime hormone that tells your body it is time to sleep, whereas magnesium helps promote a relaxation response as you wind down to sleep. There is a time and place for both. Taking a higher dose of melatonin than what your body produces (0.35 mcg/night) can override your body’s own circadian response. However, taking magnesium provides nutritional insurance to prevent deficiency, which will improve all aspects of health.

Are There Any Side Effects from Magnesium?

Excessive doses of magnesium can cause stomach upset and diarrhea. However, these are much more common with inorganic salts (oxide, chloride, and sulfate) than organic salts (glycinate, chelate, sucrosomial, malate, taurate, etc.).

Some people may experience mild drowsiness, so it’s a good idea to avoid operating machinery or driving after taking Magnesium Breakthrough until you know your response to it.

Should You Start Taking Magnesium For Sleep?

Everyone should take magnesium given that the modern lifestyle depletes it and the modern diet doesn’t provide enough. If you have suboptimal sleep, such as taking a long time to fall asleep, waking up tired, or feeling tired in the afternoon, magnesium may help improve your sleep quality.

PRIDUCT_NAME
  • Made in USA
  • GMP Certified
  • Manufacturing COA

Product Information

Product Dimensions:

  • Cap diameter: 3.6 inches
  • Bottom diameter: 3.7 inches
  • Height: 1.4 inches
  • Weight: 201 grams

Caution:

Keep out of reach of children. As with any product, discontinue immediately if adverse effects occur. Please consult a physician before beginning any new supplement, diet, training program, or if you are undergoing treatment of a medical condition.

MAGNESIUM BREAKTHROUGH
MAGNESIUM BREAKTHROUGH
MAGNESIUM BREAKTHROUGH
PRIDUCT_NAME
  • Made in USA
  • GMP Certified
  • Manufacturing COA

Product Information

Product Dimensions:

  • Cap diameter: 3.6 inches
  • Bottom diameter: 3.7 inches
  • Height: 1.4 inches
  • Weight: 189 grams

Caution:

Keep out of reach of children. As with any product, discontinue immediately if adverse effects occur. Please consult a physician before beginning any new supplement, diet, training program, or if you are undergoing treatment of a medical condition.

MAGNESIUM BREAKTHROUGH
MAGNESIUM BREAKTHROUGH
MAGNESIUM BREAKTHROUGH
PRIDUCT_NAME
  • Made in USA
  • GMP Certified
  • Manufacturing COA

Product Information

Product Dimensions:

  • Cap diameter: 3.6 inches
  • Bottom diameter: 3.7 inches
  • Height: 1.4 inches
  • Weight: 156 grams

Caution:

Keep out of reach of children. As with any product, discontinue immediately if adverse effects occur. Please consult a physician before beginning any new supplement, diet, training program, or if you are undergoing treatment of a medical condition.

MAGNESIUM BREAKTHROUGH
MAGNESIUM BREAKTHROUGH
MAGNESIUM BREAKTHROUGH

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BIOptimizers Was Born From Pain And Passion

Wade’s passion and mission for helping others optimize their health started when he witnessed his 23-year-old sister pass away from cancer. It was a heart-breaking experience that shaped his destiny. That’s when he realized that health was the most precious asset we have in this life.

Matt’s passion and purpose for helping others started when he helped his best friend lose 191 lbs in 18 months. He watched his friend’s entire life transform as a result. He went from never having a girlfriend to being married in just a couple of years.

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President

Matt Gallant

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Chief Executive Officer

Wade and Matt were both trainers working with pro athletes and other high performers. They both spent a decade in the gym helping people transform their health. Wade and Matt met in the gym, struck a friendship, and then started a business partnership that has been going strong since 2004.

That’s right, we started selling fitness programs, digestive enzymes and organic plant-based protein in 2004. Our obsession to build the best-in-class formulas and solutions just gets stronger. Our policy is, “If we can’t build the best product in that category, forget about it.”

We’re willing to go ALL IN on the formulas. What does this mean? Our average cost per bottle is 200% to 400% higher than most of our competitors. We use the optimal, effective doses of the most researched ingredients. We know that once you experience the results, you’ll be a fan of BIOptimizers for life.

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Thank YOU for helping us become one of the fastest-growing companies in America - 3 Years in a row.

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Scientific Studies
  1. “Chelated Magnesium Uses, Side Effects & Warnings.” Drugs.com, www.drugs.com/mtm/chelated-magnesium.html.
  2. Schutten, Joëlle C., et al. “Effects of Magnesium Citrate, Magnesium Oxide and Magnesium Sulfate Supplementation on Arterial Stiffness in Healthy Overweight Individuals: A Study Protocol for a Randomized Controlled Trial.” Trials, vol. 20, no. 1, 28 May 2019, https://doi.org/10.1186/s13063-019-3414-4.
  3. “Magnesium Glycinate Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD.” Www.webmd.com, www.webmd.com/drugs/2/drug-152090/magnesium-glycinate-oral/details.
  4. Uysal N, Kizildag S, Yuce Z, Guvendi G, Kandis S, Koc B, Karakilic A, Camsari UM, Ates M.Timeline (Bioavailability) of Magnesium Compounds in Hours: Which Magnesium Compound Works Best? Biol Trace Elem Res. 2019 Jan;187(1):128-136. doi: 10.1007/s12011-018-1351-9. Epub 2018 Apr 21. PMID: 29679349.
  5. Maypro. “Sucrosomial® Magnesium.” Maypro, www.maypro.com/products/sucrosomial-magnesium-a-source-of-magnesium-oxide-with-superior-bioavailability.
  6. McCarty MF. Complementary vascular-protective actions of magnesium and taurine: a rationale for magnesium taurate. Med Hypotheses. 1996 Feb;46(2):89-100. doi: 10.1016/s0306-9877(96)90007-9. PMID: 8692051.
  7. Rosenfeldt FL. Metabolic supplementation with orotic acid and magnesium orotate. Cardiovasc Drugs Ther. 1998 Sep;12 Suppl 2:147-52. doi: 10.1023/a:1007732131887. PMID: 9794088.
  8. de Baaij JH, Hoenderop JG, Bindels RJ. Magnesium in man: implications for health and disease. Physiol Rev. 2015;95(1):1-46. doi:10.1152/physrev.00012.2014
  9. Jacka FN, Overland S, Stewart R, Tell GS, Bjelland I, Mykletun A. Association between magnesium intake and in community-dwelling adults: the Hordaland Health Study. Aust N Z J Psychiatry. 2009;43(1):45-52. doi:10.1080/00048670802534408
  10. Grases G, Pérez-Castelló JA, Sanchis P, et al. Anxiety and stress among science students. Study of calcium and magnesium alterations. Magnes Res. 2006;19(2):102-106.
  11. Takase B, Akima T, Uehata A, Ohsuzu F, Kurita A. Effect of chronic stress and sleep deprivation on both flow-mediated dilation in the brachial artery and the intracellular magnesium level in humans. Clin Cardiol. 2004;27(4):223-227. doi:10.1002/clc.4960270411
  12. Boyle NB, Lawton C, Dye L. The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review. Nutrients. 2017;9(5):429. Published 2017 Apr 26. doi:10.3390/nu9050429
  13. Boyle NB, Lawton C, Dye L. The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review. Nutrients. 2017;9(5):429. Published 2017 Apr 26. doi:10.3390/nu9050429
  14. Pouteau E, Kabir-Ahmadi M, Noah L, et al. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial. PLoS One. 2018;13(12):e0208454. Published 2018 Dec 18. doi:10.1371/journal.pone.0208454
  15. Bøhmer T, Røseth A, Holm H, Weberg-Teigen S, Wahl L. Bioavailability of oral magnesium supplementation in female students evaluated from elimination of magnesium in 24-hour urine. Magnes Trace Elem. 1990;9(5):272-278.
  16. Firoz M, Graber M. Bioavailability of US commercial magnesium preparations. Magnes Res. 2001;14(4):257-262.
  17. Uysal N, Kizildag S, Yuce Z, et al. Timeline (Bioavailability) of Magnesium Compounds in Hours: Which Magnesium Compound Works Best? Biol Trace Elem Res. 2019;187(1):128-136. doi:10.1007/s12011-018-1351-9
  18. DiNicolantonio JJ, Liu J, O'Keefe JH. Magnesium for the prevention and treatment of cardiovascular disease. Open Heart. 2018;5(2):e000775. Published 2018 Jul 1. doi:10.1136/openhrt-2018-000775
  19. Boyle NB, Lawton C, Dye L. The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review. Nutrients. 2017;9(5):429. Published 2017 Apr 26. doi:10.3390/nu9050429
  20. Pouteau E, Kabir-Ahmadi M, Noah L, et al. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial. PLoS One. 2018;13(12):e0208454. Published 2018 Dec 18. doi:10.1371/journal.pone.0208454
  21. Eby GA, Eby KL. Rapid recovery from major depression using magnesium treatment. Med Hypotheses. 2006;67(2):362-370. doi:10.1016/j.mehy.2006.01.047
  22. Tarleton EK, Littenberg B, MacLean CD, Kennedy AG, Daley C. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial. PLoS One. 2017;12(6):e0180067. Published 2017 Jun 27. doi:10.1371/journal.pone.0180067
  23. Botturi A, Ciappolino V, Delvecchio G, Boscutti A, Viscardi B, Brambilla P. The Role and the Effect of Magnesium in Mental Disorders: A Systematic Review. Nutrients. 2020;12(6):1661. Published 2020 Jun 3. doi:10.3390/nu12061661
  24. Barragán-Rodríguez L, Rodríguez-Morán M, Guerrero-Romero F. Efficacy and safety of oral magnesium supplementation in the treatment of depression in the elderly with type 2 diabetes: a randomized, equivalent trial. Magnes Res. 2008;21(4):218-223.
  25. Guerrero-Romero F, Tamez-Perez HE, González-González G, et al. Oral magnesium supplementation improves sensitivity in non-diabetic subjects with resistance. A double-blind placebo-controlled randomized trial. Diabetes Metab. 2004;30(3):253-258. doi:10.1016/s1262-3636(07)70116-7
  26. Takaya J, Higashino H, Kobayashi Y. Intracellular magnesium and resistance. Magnes Res. 2004;17(2):126-136.
  27. Schnack C, Bauer I, Pregant P, Hopmeier P, Schernthaner G. Hypomagnesaemia in type 2 diabetes mellitus is not corrected by improvement of long-term metabolic control. Diabetologia. 1992;35(1):77-79. doi:10.1007/BF00400855
  28. Askari M, Mozaffari H, Jafari A, Ghanbari M, Darooghegi Mofrad M. The effects of magnesium supplementation on obesity measures in adults: a systematic review and dose-response meta-analysis of randomized controlled trials [published online ahead of print, 2020 Jul 11]. Crit Rev Food Sci Nutr. 2020;1-17. doi:10.1080/10408398.2020.1790498
  29. Zhang Y, Xun P, Wang R, Mao L, He K. Can Magnesium Enhance Exercise Performance?. Nutrients. 2017;9(9):946. Published 2017 Aug 28. doi:10.3390/nu9090946
  30. Córdova A, Mielgo-Ayuso J, Roche E, Caballero-García A, Fernandez-Lázaro D. Impact of Magnesium Supplementation in Muscle Damage of Professional Cyclists Competing in a Stage Race. Nutrients. 2019;11(8):1927. Published 2019 Aug 16. doi:10.3390/nu11081927
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