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Bloating And Gas After Every Meal?

This Could Be Just The Tip Of The Iceberg

It’s not rare for people to feel bloated, gassy and irritated after their favorite meal. But feeling bloated after eating can be a sign of a critical, underlying issue.

Living with discomfort shouldn't be something we get used to. And it’s time for you to enjoy food again and live pain-free. 

NOW YOU CAN EAT YOUR FAVORITE MEALS AND…
GET AWAY WITH IT!

While you also:  

  • Improve your digestion
  • Absorb more nutrients
  • Support muscle building
  • Relief from gases, bloating and indigestion
  • Eat out without any risk
  • Support healthy glucose uptake into cells
DID YOU KNOW THAT GLUTEN AND CASEIN ARE PROTEINS
THAT COULD WRECK DOWN YOUR DIGESTION? [1,2]

And that they’re found in almost every meal!

Unfortunately our main digestive enzymes responsible for protein degradation in the gastrointestinal tract (gastric, pancreatic, and intestinal enzymes) aren’t strong enough to digest these proteins3, making us feel bloated after eating.

That’s why Gluten Guardian contains the best enzymes for gluten sensitivity

Turning even the hardest to digest proteins into
amino acids that your body can absorb.

DID YOU KNOW THAT GLUTEN AND CASEIN ARE PROTEINS
THAT COULD WRECK DOWN YOUR DIGESTION? [1,2]

And that they’re found in almost every meal!

Unfortunately our main digestive enzymes responsible for protein degradation in the gastrointestinal tract (gastric, pancreatic, and intestinal enzymes) aren’t strong enough to digest these proteins3, making us feel bloated after eating.

That’s why Gluten Guardian contains the best enzymes for gluten sensitivity

Turning even the hardest to digest proteins into
amino acids that your body can absorb.

Peptidase DPP-IV

GLUTEN GUARDIAN'S KEY ENZYME BLEND.

When talking about “Digestive Enzymes for Casein and Gluten” this one’s your “one and done” solution. 

Peptidase DPP-IV is a potent gluten-digesting enzyme complex, made from 6 different types of protease. It’s proven to increase gluten breakdown thrice as fast than the body would naturally do3. Which also  breaks down casein, a protein that makes up 80% of milk proteins and thousands of adults can develop a sensitivity to.

Also, the combination of DPP IV with pepsin (a stomach protease) contained in Gluten Guardian works synergically for optimized gluten breakdown4.

AstraZyme

A patented protease blend that helps to break down protein at different digestion stages and pH levels, allowing the absorption of the full range of essential amino acids. 

This supplement also contains Astragallus and Ginseng extracts, plants widely used in ancient Chinese medicine, which boost the power of the contained enzymes and support the absorption of vitamins and minerals.

Backed by 17 studies that prove how Astrazyme enhances peptides absorption, essential amino acids and other nutrients like folate and omega-7 fatty acid.4

Starch Enyzme Complex

Gluten Guardian also contains a combination of 3 starch-metabolizing enzymes. They help break processed carbs and sugars and transform them into energy instead of being stored as body fat. 

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The Untold Truth About the Second Brain

Unfortunately nowadays being ‘gluten or lactose intolerant’ is an ongoing problem for millions of people globally.

But there’s something even worse than realizing you’re one of them: ignoring the fact and...

Not doing anything about it.

Because you might be ‘gluten-sensitive’ even if you’re not aware, and...

Gluten and casein can potentially affect everyone!

So, let me ask you…

Are any of these part of your everyday life?

  • Abdominal pain
  • Gas and bloating
  • Diarrhea
  • Acid reflux
  • Fatigue
  • Brain fog
  • Skin problems
  • Mood swings

Gluten Sensitive And Ignoring It?

If there’s something Gluten Guardian consumers’ have left behind are those days of waking up,  feeling sick, gassy, bloated or even exhausted. 

Wondering... “Is it the flu? Did I eat something spoiled?” 

And ignoring the fact that their favorite meals may be slowing down their metabolism due to digestive issues with gluten..

ACCORDING TO A STUDY, OVER 80% OF PEOPLE WITH CELIAC DISEASE DON'T EVEN KNOW THAT THEY HAVE IT. [5]

But now people are enjoying their new digestion by using the best digestive enzymes for gluten sensitivity:

Gluten Sensitive And Ignoring It?

If there’s something Gluten Guardian consumers’ have left behind are those days of waking up,  feeling sick, gassy, bloated or even exhausted. 

Wondering... “Is it the flu? Did I eat something spoiled?” 

And ignoring the fact that their favorite meals may be slowing down their metabolism due to digestive issues with gluten..

ACCORDING TO A STUDY, OVER 80% OF PEOPLE WITH CELIAC DISEASE DON'T EVEN KNOW THAT THEY HAVE IT. [5]

But now people are enjoying their new digestion by using the best digestive enzymes for gluten sensitivity:

Isaac Garcia
Isaac Garcia

No more heartburn or indigestion! I also feel more full
when taking the enzymes. I would highly recommend it.

Kelly R.
Kelly R.

Digestion has been SO much better!! And I feel lighter, ( I've actually lost some weight)
- I really love this product!

Jeremy H.
Jeremy H.

I have tried many different things in an effort to deal with my EXTREME gluten sensitivity
and nothing has worked until this. It's worth every penny..

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When Was The Last Time You Felt Light
And Energized After A Meal?

Most of the time we’re aware and cautious about the amount of food we ingest in order to prevent being bloated or gassy after eating,  but even by ingesting small amounts, the result is the same. 

We end up with irritation, discomfort, bloating and gas.
And that’s because we keep feeding our bodies with...

HARD TO DIGEST PROTEINS, SUCH AS GLUTEN AND CASEIN.

Even if you eat gluten-free food, most restaurant kitchens do not separate gluten-containing ingredients. This means there’s always the risk of gluten exposure anytime you eat out.

But the risk isn’t only some momentary pain!

Gluten and dairy can cause leaky gut6, allowing food fragments
to enter the bloodstream. 

What does that mean for you? 

Acne, gases, weight-gain or even other immune-related diseases, but the most common
and the one we normalize the most is having extreme fatigue after eating. 

Being tired and brain-fogged after meals are signs that your gut is working hard to digest your meals,
and that you are getting bloated from consuming your meals. 

FOOD SHOULD ENERGIZE YOU INSTEAD OF FATIGATE YOU.

When Was The Last Time You Felt Light
And Energized After A Meal?

Most of the time we’re aware and cautious about the amount of food we ingest in order to prevent being bloated or gassy after eating,  but even by ingesting small amounts, the result is the same. 

We end up with irritation, discomfort, bloating and gas.
And that’s because we keep feeding our bodies with...

HARD TO DIGEST PROTEINS, SUCH AS GLUTEN AND CASEIN.

Even if you eat gluten-free food, most restaurant kitchens do not separate gluten-containing ingredients. This means there’s always the risk of gluten exposure anytime you eat out.

But the risk isn’t only some momentary pain!

Gluten and dairy can cause leaky gut6, allowing food fragments
to enter the bloodstream. 

What does that mean for you? 

Acne, gases, weight-gain or even other immune-related diseases, but the most common
and the one we normalize the most is having extreme fatigue after eating. 

Being tired and brain-fogged after meals are signs that your gut is working hard to digest your meals,
and that you are getting bloated from consuming your meals. 

FOOD SHOULD ENERGIZE YOU INSTEAD OF FATIGATE YOU.

Why Should You Make
Gluten Guardian Part Of Your Life

Gluten Guardian supports digestive function, especially for high-carb & protein meals. It contains full-spectrum protein-digesting and carbohydrate-digesting enzymes.

Gluten Guardian can also be taken on an empty stomach to harness the benefits of systemic protein-digesting enzymes. These include promoting exercise recovery, breaking down inflammatory proteins and scar tissues, and wound healing.

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16 Gluten Sensitivity Symptoms THat Could Be A Red Flag For You [7]:

  • Abdominal pain
  • Digestive upset
  • Gas and bloating
  • Symptoms of irritable bowel syndrome, such as constipation or diarrhea
  • Acid reflux
  • Fatigue
  • Fatigue
  • Brain fog
  • Skin problems
  • Mood issues
  • Psychosis
  • Numbness
  • Unhealthy and unexplained weight loss
  • Inability to lose weight
  • Anemia
  • Autoimmune disorders
  • Aches and pains

Still Wondering If Gluten Guardian Is The Right Choice
To Forget About Bloating And Gassiness?

HERE'S EVERYTHING YOU NEED TO KNOW BEFORE GETTING GLUTEN GUARDIAN

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GLUTEN GUARDIAN® QUESTIONS:

What is the recommended dosage for Gluten Guardian®?

Take 3 capsules with water at the beginning of each meal for optimal digestion.

Do not exceed 9 capsules per day.

Consult your medical practitioner prior to starting any new supplement.

Can children take Gluten Guardian®? If so, what is the recommended dosage?

Gluten Guardian® is safe for children. The recommended dose is 1 capsule for every 50 lbs.

Consult your medical practitioner prior to starting any new supplement.

I have a clean diet, why would I need to take Gluten Guardian®?

Gluten and casein are sticky proteins that are very difficult to digest. They also tend to stimulate the immune system, which can lead to inflammatory symptoms, both inside and outside the gut. Gluten Guardian® is great for the occasions that you want to indulge in gluten-containing foods or eat out, especially if you have some sensitivity to gluten or dairy. However, it is not an approved treatment for Celiac disease, severe gluten intolerance, or allergies.

I am already taking digestive enzymes. So why do I need to take Gluten Guardian®?

Most digestive enzymes don’t contain enzymes that digest the most difficult to digest parts of gluten and casein, such as DPP-IV. Gluten Guardian® contains a high dose of DPP-IV, along with other synergistic enzymes that optimize your digestion after consuming gluten-containing meals.

DPP IV is a family of enzymes, some of which control hormones, neuronal function, and inflammation in your body. Some food substances, including but not limited to partially digested gluten and casein, may cause symptoms by inhibiting enzymes in the DPP-IV family. Some diabetic drugs increase insulin by inhibiting pancreatic DPP-IV, but also cause severe joint pain as a side effect. Therefore, some people benefit from supplementing with digestive DPP IV on a regular basis to reduce food-based DPP IV inhibitors in the gut. However, keep in mind that Gluten Guardian® is not approved to treat any disease and you should consult your physician.

How many capsules are in a Gluten Guardian® bottle?

The Gluten Guardian® bottle contains 90 capsules.

Can someone who has celiac disease take Gluten Guardian®?

Gluten Guardian® is not an approved treatment for any disease, including Celiac disease or gluten allergy. Neither is it a replacement for a gluten-free diet to manage health conditions that arise from gluten consumption. However, many well-controlled Celiacs find Gluten Guardian® to be an excellent safety net when they have foods that may have small amounts of gluten contamination. Some find that it provides significant relief after gluten exposure. However, individual responses vary widely, so you need to work with your healthcare professional to decide what’s best for you.

Is it okay for pregnant or breastfeeding mothers to take Gluten Guardian®?

Pregnant or breastfeeding mothers should consult a medical practitioner prior to starting any new supplement, diet, or training program.

Can I empty the contents of the capsule in a beverage?

The contents of the capsules can be dissolved in your beverage of choice. Doing so will not improve nor diminish absorption or the health benefits you obtain.

What is the shelf life for Gluten Guardian®?

The shelf life for Gluten Guardian® is 2 years from the manufactured date, which can be found on the bottle.

How should you store Gluten Guardian®?

Store Gluten Guardian® in a cool and dry place.

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FREQUENTLY ASKED QUESTIONS:

How is gluten broken down in the body?

Gluten is a group of proteins found in wheat. Like other proteins, it gets digested by protein-digesting enzymes called proteases. Each protease typically recognizes a certain amino acid pattern. However, gluten has an odd structure consisting of a lot of glutamine and proline, which makes it difficult for any protease other than DPP-IV to digest. 8

How do I become gluten free?

Becoming gluten-free involves cutting out bread, pasta, regular oats, and all foods that contain gluten. Gluten is found in wheat, rye, and barley. It can also come hidden in sauces, salad dressing, marinade, alcoholic drinks, or as thickeners. You will need to learn to read food labels to identify components that may contain gluten. Celiacs and people who are very sensitive have to make sure that all of their foods are made in gluten-free facilities and have never touched gluten, because even parts per million of gluten can provoke symptoms. We recommend working with a certified gluten-free practitioner.

If gluten has been causing you inflammation, you’ll likely experience less bloating, lowered inflammation, clearer skin, more energy, and less brain fog. However, keep in mind that a gluten-free diet is not for everyone or a cure-all. You should check with your healthcare practitioner to address your health issues.

What is celiac disease?

Celiac disease is an autoimmune condition found in genetically predisposed people. When people with Celiac disease consume gluten, their immune system attacks the gut lining. This typically results in severe digestive symptoms and nutritional deficiencies due to malabsorption. People with Celiac disease are at a higher risk of developing other autoimmune disease, both due to their genetics, inflammation, and leaky gut.9 Also, many people with obscure inflammatory symptoms or other autoimmune disease have undiagnosed Celiac disease. The only way to manage Celiac disease is to strictly avoid gluten. Celiacs can become very sick if their foods have touched a gluten-containing food or cooked in a container that used to have gluten.

Gluten Guardian® is not a replacement for strict gluten avoidance to manage Celiac disease. However, many Celiacs find that Gluten Guardian® helps them with occasional low-dose gluten exposure, such as when they eat out. It also helps them feel safer to have Gluten Guardian® as a safety net. Even so, individual responses may vary, so you should consult with your physician.

Although Gluten Guardian® can potently break down the immunogenic parts of gluten, it may not fully keep gluten from the gut lining. Therefore, we do not advise that Celiacs use Gluten Guardian® to liberally eat bread or pasta.

What are the symptoms of celiac disease?

Celiac disease is associated with the following conditions, although they’re not always caused by Celiac disease or gluten. Therefore, if you have these conditions that don’t respond to any other treatments, speak to your doctor about a possible Celiac diagnosis:

  • Fatigue
  • Constipation, Diarrhea, or alternating
  • Bloating and gas
  • Nausea and vomiting
  • Weight loss or inability to lose weight
  • Brain fog
  • Headache
  • Inability to focus or ADHD
  • Hormone imbalances
  • Infertility and miscarriage
  • Skin problems
  • Joint pain
  • Other autoimmune conditions
  • Symptoms of severe nutrient deficiency may also be caused by Celiac disease:

Symptoms of severe nutrient deficiency may also be caused by Celiac disease:

  • Iron deficiency anemia
  • Loss of bone density
  • Mouth ulcers
  • Tingling of hands and feet

A Celiac diagnosis may require blood tests for antibodies against gluten, genetic tests for HLA-DQ2 and HLA-DQ8 genes, and colonoscopy. Visible damages to the small intestine lining on colonoscopy would confirm Celiac disease.10

Non-Celiac Gluten Sensitivity (also called Gluten Sensitivity or Intolerance) refers to any other inflammatory symptoms caused by gluten consumption that are not caused by autoimmunity.11 It is a less-defined and less recognized condition than Celiac disease.

If you are gluten-sensitive rather than Celiac, you may not have antibodies against gluten or visible damages in your gut lining through endoscopy. However, you will experience significant relief of some inflammatory symptoms when you go gluten-free, and the symptoms will return once you start to eat gluten again.

Gluten allergy is one of the most common food allergies that can be diagnosed with the presence of IgE antibodies in the blood. Like other food allergies, it can result in acute and severe allergic symptoms such as runny nose, hives, asthma, headache, stomachache, vomiting, diarrhea, or anaphylaxis.

In all of these cases, the best way to manage it is to strictly and completely avoid gluten.

What foods trigger celiac disease?

There are 3 components that trigger Celiac disease:

Genetic predispositions, such as the HLA-DQ2 and HLA-DQ8 genes, and family history of autoimmunity.

A life event that triggers autoimmunity, such as infections, stress or trauma, pregnancy, or surgery

Gluten consumption

Gluten-containing foods may include (may not be exhaustive list):

  • Wheat
  • Rye
  • Barley
  • Einkorn
  • Spelt
  • Semolina
  • Beer
  • Malt
  • Brewer’s yeast
  • Wheat starch
  • Farro
  • Graham
  • Kamut
  • Bread and all baked goods
  • Pasta
  • Breakfast cereals
  • Pancakes, waffles, crepes, and biscuits
  • Croutons
  • Flour tortillas
  • Soy sauce
  • Salad dressing and marinade*
  • Soup*
  • Starch
  • Grain alcohol*

*Depending on the ingredient. Best to choose the certified gluten-free option.

What is casein?

Casein is a protein that comprises 82% majority of milk protein. Like gluten, it is very difficult to digest with normal digestive enzymes due to its structure. Cow’s milk in North America tends to be A1 milk, with digestion resistant fragments that can act like opiates (casomorphins). A1 casomorphins can provoke inflammation, causing digestive problems  and inflammatory health conditions.12 Therefore, A1 milk can cause milk intolerance that is not caused by lactose intolerance.13 There is no medical test that can diagnose casein intolerance other than elimination-challenge.

Casein allergy is a food allergy that can be diagnosed with the skin prick test or blood test for IgE antibodies against milk. People with milk allergy will experience allergic symptoms such as hives, asthma, or anaphylaxis.

The DPP-IV enzyme in Gluten Guardian® can help completely break down the casein in your diet, thus reducing its immunogenicity. Other enzymes in Gluten Guardian® also help ensure optimal digestion for occasional indulgence.14 However, Gluten Guardian® is not approved to treat dairy intolerance or allergies.

If you develop skin problems, bloating, or any inflammatory symptoms with dairy consumption, you should avoid dairy and casein. If you struggle to get enough proteins for your fitness goals, consider taking MassZymes with every meal to maximize your protein absorption.

What is proteolytic enzyme?

Proteolytic (proteo = protein, lytic = break) enzymes or proteases digest proteins into peptides and eventually into amino acids. Pepsin is secreted in the stomach, whereas most other proteases are produced by the pancreas and secreted in the small intestine. These enzymes are important because incompletely digested proteins means less amino acids available for your body. It also means that some of these protein fragments could contribute to food allergies or other food-related inflammation. Incompletely digested proteins and unabsorbed amino acids will further get fermented by the gut bacteria. The protein and amino acid fermentation process tend to create unhealthy byproducts, so it is best to ensure that most of the protein you eat is available to you rather than your gut bacteria.15

Proteolytic enzymes are also important for wound healing, resolution of inflammation, and exercise recovery. When consumed with foods, proteolytic enzymes help digest food in the gut. However, when consumed on an empty stomach, plant proteolytic enzymes, such as those in AstraZyme, can be absorbed into the bloodstream. These plant enzymes can also support your natural healing processes from injuries, inflammation, or exercise training.

What is amylase and its function?

Amylases are enzymes that digest starch into maltose and subsequently glucose. Glucose is the sugar that can be absorbed and used as fuel every cell in your body.

What does amylase help our bodies do?

If you have some ongoing imbalances in your gut bacteria or don’t usually eat a lot of carbs, a high-carb meal can cause bloating due to inflammation and bacterial fermentation. Gluten Guardian® contains three different types of amylase, which function at a full-spectrum of pH, to ensure that all the carbs get broken down into glucose.

What is protease?

Proteolytic (proteo = protein, lytic = break) enzymes or proteases digest proteins into peptides and eventually into amino acids. Pepsin is secreted in the stomach, whereas most other proteases are produced by the pancreas and secreted in the small intestine. These enzymes are important because incompletely digested proteins means less amino acids available for your body. It also means that some of these protein fragments could contribute to food allergies or other food-related inflammation. Incompletely digested proteins and unabsorbed amino acids will further get fermented by the gut bacteria. The protein and amino acid fermentation process tend to create unhealthy byproducts, so it is best to ensure that most of the protein you eat is available to you rather than your gut bacteria.

Proteolytic enzymes are also important for wound healing, resolution of inflammation, and exercise recovery. When consumed with foods, proteolytic enzymes help digest food in the gut. However, when consumed on an empty stomach, plant proteolytic enzymes, such as those in AstraZyme, can be absorbed into the bloodstream. These plant enzymes can also support your natural healing processes from injuries, inflammation, or exercise training.

What is protease used for?

Proteases are important to dissolve blood clots (they thin the blood also), and plant proteases help dissolve blood clots or adhesions that result from initial wound closures. Plant proteases in supplemental form do not help with cell division, unfolded protein responses, or autophagy.

Why are protease enzymes important?

The acid-alkalinity of the blood is very narrowly regulated. Any more than 0.1 change in pH can result in near-death sickness or death. The acid/alkalinity that's discussed in health is actually the acid/alkalinity of the urine. However, the theory that either one is healthy has been debunked. There is no scientific basis behind alkalinity of the blood leading to anxiety or insomnia.

What is lipase?

Lipase is an enzyme that helps break down fat into glycerol and three fatty acid molecules.

What is DPP IV?

DPP IV or DPP 4 stands for prolyl dipeptidyl peptidase IV. It is a family of enzymes that cut behind proline and alanine. Proline is an odd amino acid that has a rigid ring structure and introduces a kink into the protein, making it impossible for most proteases to digest proteins that contain a lot of proline. The DPP IV group of enzymes is present throughout the human body, helping to activate some peptide hormones, other enzymes, inflammatory substances, and neurotransmitters.

Some drugs, and incompletely digested peptides of gluten and casein can overwhelm and block the natural DPP IV enzymes that participate in these other biological processes. For example, Substance P is a 10 amino acid neuropeptide that controls pain sensation and anxiety, and is deactivated by a DPP IV. For sensitive people, consuming dairy and gluten on a regular basis can block DPP IV and increase substance P, leading to increased pain.16

People who suffer from elevated substance P may benefit from supplementing with a high-dose digestive DPP IV on a regular basis to reduce any food substance that may inhibit their own natural DPP IV. However, Gluten Guardian® is not approved to treat any disease and you should consult your physician, especially if you are taking medications.

Where is DPP 4 Produced?

The DPP IV in Gluten Guardian® comes from a fungus Aspergillus, which is used in oriental cultures to ferment soybeans.

The Aspergillus DPP IV has been shown to digest gluten in the gut of healthy people.17 People who took the enzyme had no trace of gluten left in their stomach at 1 hour, compared to 3 hours with the placebo. Also, the combination of DPP IV with pepsin (a stomach protease), such as found in Gluten Guardian®, can significantly reduce more gluten peptides than either enzyme alone.18

The other DPP IV family enzymes found in your body are present on the surface of the linings of the gut and kidneys, blood vessels, liver and pancreas, glandular cells, and white blood cells.19

Can taking digestive enzymes be harmful?

Digestive enzymes exist within your body and digestive enzyme supplements are generally safe. However, you should avoid digestive enzymes if you have gastritis or ulcer in your digestive system. Also, digestive enzymes may interact with diabetes medications and blood thinners, so you should always consult your doctors if you are on any medications.

Are supplements to digest gluten safe and useful?

Peptidase DPP IV is generally safe. Also, a randomized clinical trial demonstrated that the gluten-digesting enzyme can significantly digest most gluten in the stomach before the food reaches the small intestine.20While gluten-digesting enzymes are not treatments for Celiac disease, it helps with digesting gluten and casein in the gut.

Why is gluten so bad for you?

There are many reasons why gluten is bad for you. Plants can’t run away, so they create proteins that are toxic to animals who eat them. Gluten is one such protein that always stimulates your immune system and opens your gut barrier.

People who are optimally healthy have the immune systems that can ignore the wheat component and control disease-causing inflammation. However, suboptimal conditions, such as having high stress, unhealthy gut, dysbiosis, unhealthy diets, low enzymes, and poor sleep will allow gluten to become a problem.

The Benefits of A Strong Gluten Guardian Supplement Backed By Science

GETTING ALL OF THESE FORMS OF ENZYMES, IN THE OPTIMUM DOSE
UPGRADES VIRTUALLY EVERY FUNCTION IN YOUR BODY

  • 1 Am J Gastroenterol 2021;116:225–226. https://doi.org/10.14309/ajg.0000000000001119; published online January 19, 2021
  • 2 Fasano A. Intestinal permeability and its regulation by zonulin: diagnostic and therapeutic implications. Clin Gastroenterol Hepatol. 2012;10(10):1096-1100. doi:10.1016/j.cgh.2012.08.012
  • 3 Salden BN, Monserrat V, Troost FJ, et al. Randomised clinical study: Aspergillus niger-derived enzyme digests gluten in the stomach of healthy volunteers. Aliment Pharmacol Ther. 2015;42(3):273-285. doi:10.1111/apt.13266
  • 4 NuLiv Science AstraGin™ Product Dossier, Section 6. https://www.docdroid.net/rA01t9O/nuliv-science-astragin-research.pdf#page=4
  • 5 Choung, R. S., Larson, S. A., Khaleghi, S., Rubio-Tapia, A., Ovsyannikova, I. G., King, K. S., Larson, J. J., Lahr, B. D., Poland, G. A., Camilleri, M. J., & Murray, J. A. (2017). Prevalence and Morbidity of Undiagnosed Celiac Disease From a Community-Based Study. Gastroenterology, 152(4), 830–839.e5. https://doi.org/10.1053/j.gastro.2016.11.043
  • 6 Fasano A. All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases. F1000Res. 2020;9:F1000 Faculty Rev-69. Published 2020 Jan 31. doi:10.12688/f1000research.20510.1
  • 7 Fasano A. Intestinal permeability and its regulation by zonulin: diagnostic and therapeutic implications. Clin Gastroenterol Hepatol. 2012;10(10):1096-1100. doi:10.1016/j.cgh.2012.08.012
  • 8 Salden BN, Monserrat V, Troost FJ, et al. Randomised clinical study: Aspergillus niger-derived enzyme digests gluten in the stomach of healthy volunteers. Aliment Pharmacol Ther. 2015;42(3):273-285. doi:10.1111/apt.13266
  • 9 Lauret E, Rodrigo L. Celiac disease and autoimmune-associated conditions. Biomed Res Int. 2013;2013:127589. doi:10.1155/2013/127589
  • 10 Celiac disease - Diagnosis and treatment - Mayo Clinic. Mayoclinic.org. Accessed February 23, 2021.
  • 11 Lundin KE. Non-celiac gluten sensitivity - why worry?. BMC Med. 2014;12:86. Published 2014 May 23. doi:10.1186/1741-7015-12-86
  • 12 Brooke-Taylor S, Dwyer K, Woodford K, Kost N. Systematic Review of the Gastrointestinal Effects of A1 Compared with A2 β-Casein. Adv Nutr. 2017;8(5):739-748. Published 2017 Sep 15. doi:10.3945/an.116.013953
  • 13 Pal S, Woodford K, Kukuljan S, Ho S. Milk Intolerance, Beta-Casein and Lactose. Nutrients. 2015;7(9):7285-7297. Published 2015 Aug 31. doi:10.3390/nu7095339
  • 14 Nongonierma AB, FitzGerald RJ. Susceptibility of milk protein-derived peptides to dipeptidyl peptidase IV (DPP-IV) hydrolysis. Food Chem. 2014;145:845-852. doi:10.1016/j.foodchem.2013.08.097
  • 15 Oliphant K, Allen-Vercoe E. Macronutrient metabolism by the human gut microbiome: major fermentation by-products and their impact on host health. Microbiome. 2019;7(1):91. Published 2019 Jun 13. doi:10.1186/s40168-019-0704-8
  • 16 Busek P, Stremenová J, Krepela E, Sedo A. odulation of substance P signaling by dipeptidyl peptidase-IV enzymatic activity in human glioma cell lines. Physiol Res. 2008;57(3):443-449.
  • 17 Salden BN, Monserrat V, Troost FJ, et al. Randomised clinical study: Aspergillus niger-derived enzyme digests gluten in the stomach of healthy volunteers. Aliment Pharmacol Ther. 2015;42(3):273-285. doi:10.1111/apt.13266
  • 18 Ehren J, Morón B, Martin E, Bethune MT, Gray GM, Khosla C. A food-grade enzyme preparation with modest gluten detoxification properties. PLoS One. 2009;4(7):e6313. Published 2009 Jul 21. doi:10.1371/journal.pone.0006313
  • 19 Deacon CF. Physiology and Pharmacology of DPP-4 in Glucose Homeostasis and the Treatment of Type 2 Diabetes [published correction appears in Front Endocrinol (Lausanne). 2019 May 03;10:275]. Front Endocrinol (Lausanne). 2019;10:80. Published 2019 Feb 15. doi:10.3389/fendo.2019.00080
  • 20 König J, Holster S, Bruins MJ, Brummer RJ. Randomized clinical trial: Effective gluten degradation by Aspergillus niger-derived enzyme in a complex meal setting. Sci Rep. 2017;7(1):13100. Published 2017 Oct 12. doi:10.1038/s41598-017-13587-7