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  • 100% plant-based betaine HCL and full-spectrum digestive enzymes
  • Helps restore healthy stomach acid levels
  • Improves mineral, vitamin B12, and amino acid absorption
  • Better digestion, gut movement, and detoxification
  • Relieves bloating, gas, belching, indigestion, post-meal fatigue, and stomach heaviness or discomfort after meals
  • Improves exercise recovery and muscle growth with better protein digestion (when combined with the right diet and training)
  • Promotes healthy function of the valve between esophagus and stomach, which may help with acid reflux and heartburn
  • Promotes healthy stomach acid protection against food-borne infections



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Due to high demand, we recently ran out of Magnesium Breakthrough but we are back in FULL STOCK. Be aware, due to extreme demand it can take 3-5 days to ship it out. We appreciate your patience and understanding.

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  • 100% plant-based betaine HCL and full-spectrum digestive enzymes
  • Helps restore healthy stomach acid levels
  • Improves mineral, vitamin B12, and amino acid absorption
  • Better digestion, gut movement, and detoxification
  • Relieves bloating, gas, belching, indigestion, post-meal fatigue, and stomach heaviness or discomfort after meals
  • Improves exercise recovery and muscle growth with better protein digestion (when combined with the right diet and training)
  • Promotes healthy function of the valve between esophagus and stomach, which may help with acid reflux and heartburn
  • Promotes healthy stomach acid protection against food-borne infections
Frequently Bought Together

Why You Should Get Our Betaine HCl

  • All-natural and 100% plant-based betaine hydrochloride and full-spectrum digestive enzyme blend
  • Mineral-enhanced with a full-spectrum mineral complex to provide cofactors to digestive enzymes and correct deficiencies
  • Free of pork-derived pepsin, which can irritate the esophagus (the tube between the mouth and the stomach) in people with heartburn
  • Optimizes the absorption of important minerals including iron, calcium, magnesium, zinc, copper, and manganese
  • Promotes healthy gut movement, bile flow, and enzymatic secretions
  • Helps maximize protein digestion and assimilation in the stomach, which improves exercise recovery and muscle building results
  • Reduces incomplete digested proteins that can stimulate the immune system or cause leaky gut
  • Supports the stomach’s natural ability to protect against foodborne infections, including bacteria, viruses, yeasts, and parasites
  • Supports natural protection against bacteria or yeast fermentation in the upper gut
  • Relieves indigestion, gas, bloating, belching, and fatigue after meals
  • Supports healthy closure of the valve between the stomach and esophagus
  • Enhances digestion and nutrient absorption when taken with meals
  • 100% satisfaction guarantee with respect to quality, purity, potency, and effectiveness
  • Produced in small batches with medical-grade natural ingredients
  • Improve Digestion and Heartburn by Supporting Stomach Acids With HCL Supplement

    Though most assume that heartburn and acid reflux are a result of too much stomach acid, these are actually symptoms of low stomach acid. One of the low stomach acid symptoms is heartburn and acid reflux. It is counterintuitive because acid reflux can allow the acid to irritate your esophagus and throat. However, the valve between your esophagus and stomach closes in response to enough acidity levels in the stomach.If the valve doesn’t close properly, you have insufficient stomach acid production.

    Unfortunately, most people reach for antacids or stomach acid-blocking drugs, which further reduce stomach acid levels. While these drugs do curb the symptoms and allow the esophagus to heal, they do not fix the root cause of acid reflux and heartburn. Instead, they cause further problems due to low stomach acid, such as nutrient deficiencies, improper gut movement, and increased risk of foodborne illnesses.

    To address the heartburn and acid reflux, it is best to figure out the root causes.Identify foods and situations that trigger the symptoms and avoid them. Then, support healthy stomach acid levels with a betaine hydrochloride supplement like HCL Breakthrough so the valve between the stomach and esophagus can work naturally. This will also prevent other long-term health risks from having no stomach acid.


Betaine HCL, Enzyme Blend (Protease 3.0, Protease 4.5, Amylase, Lipase, Cellulose), Trace Mineral

Other Ingredients: Rice Extract, Capsule (Vegetable Cellulose and Water).

HCL Breakthrough Benefits

  1. Promotes Healthy Digestive Function

    Your stomach acid is critical for healthy digestion by:

    • Loosening up the chemical structures of your food to make them accessible to digestive enzymes
    • Activating protein-digesting enzymes in the stomach
    • Stimulating the closure of the valve that prevents stomach acid from backflowing into your esophagus

    Low stomach acid, which tends to happen with aging and stress, can have ripple effects throughout the digestive system and thus the body. Without enough stomach acid, it takes your body significantly more energy and enzymes to digest food.

    People with low stomach acid tend to struggle with bloating, indigestion, post-meal fatigue, acid reflux and heartburn. Many also have low appetite and nutrient deficiencies. In some cases, incompletely digested proteins can contribute to leaky gut or become food allergies.

    HCL Breakthrough supports healthy stomach acid levels to ensure optimal digestion and reduce digestive discomfort.

  2. Promotes Healthy Gut Movement

    Once your food leaves the stomach, the acidity stimulates a wave-like gut movement, along with pancreatic enzyme and bile secretion. Therefore, inadequate stomach acid can cause sluggish gut movement and insufficient overall digestion, which create a perfect environment for bacteria and yeast overgrowth.

    A classic symptom of slow gut movement is constipation and long transit time. Worse yet, when the yeast and bacteria ferment food in the small intestine, it can cause gas and bloating. Small intestine bacterial overgrowth (SIBO) is also associated with many chronic health conditions including fibromyalgia, anxiety, and depression.

    For most people, improving stomach acid with a high-quality betaine HCl supplement like HCl Breakthrough can promote healthy gut movement. However, if you may have SIBO, you’ll need to see a qualified practitioner for testing, diagnosis, and treatments. While restoring healthy stomach acid levels should be a key part of any gut healing protocol, HCL Breakthrough is not FDA approved to treat or diagnose any disease.

  3. Improves Mineral and Vitamin B12 Absorption

    Stomach acid is important for the absorption of essential minerals including iron, calcium, zinc, magnesium, copper, and manganese. It also activates intrinsic factor, which is necessary for vitamin B12 absorption.

    People with inadequate stomach acid often become deficient in these minerals, which may manifest as iron-deficiency anemia, reduced bone density, and weakened immune system. You can supplement with these minerals but if you can’t absorb them, you’ll be wasting money on the mineral supplements.

    By supporting healthy stomach acid levels, HCL Breakthrough can help improve the absorption of these key minerals and vitamin B12. Many of our users find it helpful to add HCL Breakthrough along with high-iron foods and supplements to increase their iron levels.

  4. Improves Protein Digestion and Absorption

    Gastric acid secretion plays a key role in helping to denature proteins, which open up their chemical structure and make them more easily accessible to enzymes. Also, inside the stomach, the acid activates digestive enzymes including pepsin and rennin. The lack of stomach acid can reduce these steps, leading to poor protein digestion.

    Many people with low stomach acid feel stomach heaviness or are tired after meals. They may also struggle to build muscles because they cannot effectively digest and absorb proteins.

    Restoring stomach acid with HCL Breakthrough can ensure healthy protein digestion, which will relieve post-meal fatigue and heaviness. If you are working to gain muscles, you may also get better results by adding HCL Breakthrough.

  5. Support the Stomach’s Natural Ability to Protect Against Food-Borne Infections

    One of the critical roles your stomach acid plays is to sterilize your stomach content. The acidity kills most yeast, bad bacteria, and parasites, which are opportunistic infections. Low stomach acid leaves the door wide open for these infections, which may increase your risk of food-borne illnesses and chronic gut infections.

    By increasing stomach acidity, HCL Breakthrough improves your stomach’s natural ability to kill these infections before they take hold in your body.

How Do Hydrochloric Acid Supplements Work?

Betaine is a B-vitamin found in high concentration in beets. Betaine hydrochloride (HCl) is a salt of betaine and HCL. Once in the stomach, it releases the hydrochloric acid, which is the same as your stomach acid.

In a clinical study of healthy volunteers, betaine HCL supplements effectively reduced stomach pH by about 4.5 within about 30 minutes.

When to Take Betaine HCL?

Most people can use some stomach acid support because stress and aging reduces stomach acid. If you experience indigestion, acid reflux, GERD, stomach discomfort, or feeling fatigue after meals, regular use of betaine HCL with meals may provide some relief. Also, if you are low in some minerals or vitamin B12, it is a good idea to support your stomach acid levels with betaine HCL.

Your stomach naturally releases stomach acid about 30 minutes into your meal. It is, therefore, best to take HCL Breakthrough with food.

Ultimate Digestive Solution
Ultimate Digestive Solution
Ketogenic Diet
Ketogenic Diet
High Protein Meal
High Protein Meal
Muscle Building High Calorie Stack
Muscle Building High Calorie Stack
Eating in Foreign Countries
Eating in Foreign Countries
Eliminating Parasites
Eliminating Parasites
The Perfect Meal
The Perfect Meal
Ultimate Biological Optimization Program
Ultimate Biological Optimization Program

HCL Breakthrough Questions:

Why doesn't HCL Breakthrough have pepsin in it?

The only sources of pepsin available are from the stomachs of animals, such as pigs or cows. Some people are allergic to pork or beef, or have dietary restrictions that don't allow these foods.

People with low stomach acid are more likely to develop acid reflux or stomach ulcers. Among these people, the damage to the mucosa and stomach lining are caused by pepsin more than the stomach acid itself. Therefore, we chose another form of plant-based proteases instead.

What are the benefits of using HCL Breakthrough?

Nowadays, most people suffer from low stomach acid and suboptimal digestion due to:

  • Aging
  • Poor eating hygiene, such as eating distracted or in a hurry, and not chewing food properly
  • Deficiencies of minerals that are important for the production of stomach acid, such as zinc
  • Overconsumption of foods that may inhibit digestive enzymes, such as dairy and grains
  • Coffee and tea can neutralize stomach acid and inhibit digestive enzymes
  • Food allergies and sensitivities

Other than digestion, stomach acid is important for sterilizing your foods before it reaches further stages of your stomach. Also, the acidity triggers the secretions of digestive enzymes and bile, and wave-like gut movement that moves your food along. Having low stomach acid can result in overall poor digestion and gut movement, and possibly overgrowth of gut pathogens.

HCL Breakthrough can increase stomach acid and jumpstart more natural HCL production. It also contains a comprehensive combination of digestive enzymes to further help optimize digestion. The benefits of HCL Breakthrough include:

  • Better digestion
  • Relief from bloating, indigestion, belching, or post-meal fatigue
  • Better absorption of nutrients that require stomach acid to absorb, such as iron and vitamin B12
  • Healthier gut movement
How can I tell if I have low HCL?

People with low stomach acid tend to have some nutrient deficiencies and digestion symptoms. For example, they may feel a heavy sensation in their stomach and bloating, especially after meat-heavy meals.

What can you expect when you begin using HCL Breakthrough?

You should start from 1 capsule and gradually increase the dosage until you start to feel your digestive symptoms improve, as long as you don’t experience any negative symptoms.

Once you reach your optimal dose, you will immediately experience:

  • Better digestion - no heavy “brick in the stomach” sensation
  • Better post-meal energy levels
  • Relief from stomach discomfort, bloating, indigestion, belching, or burping
  • Better nutrient absorption

Within a few weeks, you may observe the improvement in your nutrification (nutrient absorption and assimilation), even though you’re eating the exact same food. For example, you may feel more energy as you absorb more iron. Or you may get better gains with your muscle mass from improved protein digestion.

Can children take HCL Breakthrough? If so, what is the suggested dosage?

HCL Breakthrough is not recommended for children.

Can you empty the contents of the HCL Breakthrough capsule in your beverage?

HCL can be corrosive to teeth and irritate sensitive tissue. Therefore, HCL Breakthrough capsules should not be dissolved in beverages.

What is the recommended dosage for HCL Breakthrough?

The recommended dosage for HCL Breakthrough is 1 capsule with each meal or within 30 minutes of eating a meal. Dosage information can be found on the bottle’s label.

Consult your medical practitioner prior to starting any new supplement, especially if you have a medical condition.

When is the best time to take HCL Breakthrough?

The optimal time to take HCL Breakthrough is 30 minutes after your meal.

Taking HCL Breakthrough before a meal may turn off stomach acid production for this meal as it may create a false experience of heartburn.

How should HCL Breakthrough be stored?

Store HCL Breakthrough in a cool and dry place.

How many capsules are in a HCL Breakthrough bottle?

HCL Breakthrough bottles contain 90 capsules.

  • Made in USA
  • GMP Certified
  • Manufacturing COA

Product Information

Product Dimensions:

  • Cap diameter: 1.5 inches
  • Bottom diameter: 2 inches
  • Height: 4 inches
  • Weight: 2.85 ounces


Do not use if ulcer or gastritis are present.


HCL BREAKTHROUGH - 365-Day Money Back Guarantee

All BIOptimizers products come with a 365-Day Money Back Guarantee. If you are not completely satisfied with your BIOptimizers product for any reason between today and 365 days from now, just send back your remaining unopened bottles of the product and we'll give you a full refund (minus the cost of shipping and handling). If you open a second bottle, you no longer qualify for any guarantee. Reach out to our customer happiness team and they will take complete care of it.

365 Money-Back Guarantee

Why BIOptimizers Is A Different Kind Of Company

  • "BEST IN CLASS" guarantee: Our mission is focused on customer obsession. If after trying our products you don't feel we are the BEST IN CLASS, we will refund your money.
  • We work with 5 world-class formulators to create the best in class formulas
  • Customers love us: 5000+ positive product reviews
  • 99.3% customer satisfaction
  • We have helped over 570,000 legendary customers optimize their health since 2004
  • The 365 Day “Best Product Ever Or Your Money Back” Guarantee
  • One of the fastest growing companies in the USA - 2 years in a row
  • Experienced customer service: our happy health concierges are happy to help via phone at (800) 719-2467 or email [email protected]

BIOptimizers Was Born From Pain And Passion

Wade’s passion and mission for helping others optimize their health started when he witnessed his 23-year-old sister pass away from cancer. It was a heart-breaking experience that shaped his destiny. That’s when he realized that health was the most precious asset we have in this life.

Matt’s passion and purpose for helping others started when he helped his best friend lose 191 lbs in 18 months. He watched his friend’s entire life transform as a result. He went from never having a girlfriend to being married in just a couple of years.

Wade Lightheart

Wade Lightheart


Matt Gallant

Matt Gallant

Chief Executive Officer

Wade and Matt were both trainers working with pro athletes and other high performers. They both spent a decade in the gym helping people transform their health. Wade and Matt met in the gym, struck a friendship, and then started a business partnership that has been going strong since 2004.

That’s right, we started selling fitness programs, digestive enzymes and organic plant-based protein in 2004. Our obsession to build the best-in-class formulas and solutions just gets stronger. Our policy is, “If we can’t build the best product in that category, forget about it.”

We’re willing to go ALL IN on the formulas. What does this mean? Our average cost per bottle is 200% to 400% higher than most of our competitors. We use the optimal, effective doses of the most researched ingredients. We know that once you experience the results, you’ll be a fan of BIOptimizers for life.

Matt & Wade Matt & Wade
Matt & Wade Matt & Wade

Thank YOU for helping us become one of the fastest-growing companies in America - 2 Years in a row.

Thank you for trusting us with your health.


CEO/Co-founder of BIOptimizers


Scientific Studies
  1. Ghoshal UC, Shukla R, Ghoshal U. Small Intestinal Bacterial Overgrowth and Digestive problems: A Bridge between Functional Organic Dichotomy. Gut Liver. 2017;11(2):196-208. doi:10.5009/gnl16126
  2. Lydiard RB. Digestive problems, anxiety, and depression: what are the links?. J Clin Psychiatry. 2001;62 Suppl 8:38-47.
  3. Yago MR, Frymoyer AR, Smelick GS, et al. Gastric reacidification with betaine HCL in healthy volunteers with hypochlorhydria. Mol Pharm. 2013;10(11):4032-4037. doi:10.1021/mp4003738

*These statements have not been evaluated by the Food and Drug Administration. Probiotic supplements are not drugs and therefore are not intended to diagnose, treat, cure, or prevent any disease or health condition.